ArticleAddictive behaviors2021
Optimizing screening for depression, anxiety disorders, and post-traumatic stress disorder in inpatient addiction treatment: A preliminary investigation.
Article in Addictive behaviors, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
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Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.
- Generalized Anxiety Disorder 7-item (GAD-7) and 2-item (GAD-2) scales for detecting anxiety disorders in adults.The Cochrane database of systematic reviews · 2025Pooled it
- Effects of participation in a large, online community for substance use disorder recovery: A naturalistic, longitudinal study.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026Article
- The Fagerström Test for Nicotine Dependence-Smokeless Tobacco: Exploring the Intricate Relationship between Smokeless Tobacco Dependence and Periodontal Status.International journal of preventive medicine · 2026Article
- Beyond one-cutoff-fits-all: determining cutoff values for the PTSD checklist for DSM-5 (PCL-5).European journal of psychotraumatology · 2025Article
- Diagnostic validity of drinking behaviour for identifying alcohol use disorder: Findings from a representative sample of community adults and an inpatient clinical sample.Addiction (Abingdon, England) · 2025Article
- Rasch analysis of DSM-5 alcohol use disorder in a large inpatient sample.Alcohol, clinical & experimental research · 2025Article
- Using Measurement-Based Care as a Precision Medicine Strategy for Substance Use Disorders.Current psychiatry reports · 2024Review
- Characterizing clinical heterogeneity in an inpatient service treating mental, substance use and concurrent disorders.PLOS mental health · 2024Article
- Examining the Potential Impact of Recreational Cannabis Legalization on Individuals Receiving Treatment for Substance Use Disorder: An Interrupted Time Series Study in Guelph, Ontario, Canada.Cannabis (Albuquerque, N.M.) · 2024Article
- Initial insights from a quality improvement initiative to develop an evidence-informed young adult substance use program.Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent · 2023Article
- The Posttraumatic Stress Disorder (PTSD) Checklist for DSM-5: A Systematic Review of Existing Psychometric Evidence.Clinical psychology : a publication of the Division of Clinical Psychology of the American Psychological Association · 2023Article
- Hazardous drinking and alcohol use disorders.Nature reviews. Disease primers · 2022Review
- Unique and Transdiagnostic Dimensions of Reward Functioning in Attention-Deficit/Hyperactivity Disorder and Alcohol Use Disorder Symptoms.Alcohol and alcoholism (Oxford, Oxfordshire) · 2022Article
- Psychometric evaluation of the treatment entry questionnaire to assess extrinsic motivation for inpatient addiction treatment.Drug and alcohol dependence reports · 2022Article
- Characterizing Clinical Heterogeneity in a Large Inpatient Addiction Treatment Sample: Confirmatory Latent Profile Analysis and Differential Levels of Craving and Impulsivity.Substance abuse : research and treatment · 2022Article
- Validation of brief screening measures for depression and anxiety in young people with substance use disorders.Journal of affective disorders · 2021Article
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Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
objectiveSubstance use disorders (SUD) are frequently comorbid with other psychiatric conditions, but a comprehensive diagnostic assessment is often not feasible clinically. Efficient psychometrically-validated screening tools exist for commonly comorbid conditions, but cutoff accuracies have typically not been evaluated in addiction treatment settings. This study examined the performance of several widely-used screening measures in relation to diagnostic status from a clinical interview to identify and validate cutoff scores in an inpatient SUD treatment setting.
methodParticipants were 99 patients in a large residential SUD treatment program in Ontario, Canada. Participants completed a screening battery, including the Patient Health Questionnaire - 9 (PHQ-9), Generalized Anxiety Disorder - 7 (GAD-7), and Post-Traumatic Stress Disorder Checklist-5 (PCL-5), and underwent a semi-structured diagnostic clinical interview. Receiver operating characteristic curves were used to determine optimal cutoff scores on the screening tool against the interview-based diagnosis.
resultsArea under the curve (AUC) was statistically significant for all screens and were as follows: PHQ-9 = 0.70 (95% CI = 0.59-0.80), GAD-7 = 0.74 (95% CI = 0.63-0.84), and PCL-5 = 0.79 (95% CI = 0.66-0.91). The optimal accuracy cutoff scores based on sensitivity and specificity were: PHQ-9 ≥ 16, GAD-7 ≥ 9, the PCL-5 ≥ 42.
conclusionsIn general, the candidate screeners performed acceptably in this population. However, the optimal cutoff scores were notably higher than existing guidelines for depression and PTSD, potentially due to the general elevations in negative affectivity among individuals initiating SUD treatment. Further validation of these cutoff values is warranted. PUBLIC HEALTH SIGNIFICANCE: This study provides modified screening cutoff scores for major depression, anxiety disorders, and post-traumatic stress disorder in addiction treatment settings.
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