Evidence map›Paper›PMID 32978685›Full record

ReviewReviews in endocrine & metabolic disorders2021

PRRT: identikit of the perfect patient.

M Albertelli, A Dotto, C Di Dato, P Malandrino, R Modica, A Versari, A Colao, D Ferone, A Faggiano, NIKE

Abstract readReview
In one paragraph

Review in Reviews in endocrine & metabolic disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Efficacy and safety ofFrontiers in oncology · 2022
    Pooled it
  2. Article
  3. Normal organ [European journal of nuclear medicine and molecular imaging · 2026
    Article
  4. Review
  5. Review
  6. Review
  7. Article
  8. Role ofFrontiers in medicine · 2025
    Article
  9. Article
  10. Non-[Pharmaceuticals (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

M AlbertelliEndocrinology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
A DottoEndocrinology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
C Di DatoEndocrinology, Department of Experimental Medicine, "Sapienza", University of Rome, Rome, Italy.
P MalandrinoEndocrinology, Department of Clinical and Experimental Medicine, Garibaldi-Nesima Medical Center, University of Catania, Catania, Italy.
R ModicaEndocrinology, Department of Clinical Medicine and Surgery, "Federico II" University of Napoli, Napoli, Italy.
A VersariNuclear Medicine, Azienda Ospedaliera Santa Maria Nuova-IRCCS Reggio Emilia, Reggio Emilia, Italy.
A ColaoEndocrinology, Department of Clinical Medicine and Surgery, "Federico II" University of Napoli, Napoli, Italy.
D FeroneEndocrinology Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy.
A FaggianoEndocrinology, Department of Experimental Medicine, "Sapienza", University of Rome, Rome, Italy. antiongiulio.faggiano@uniroma1.it.ORCID http://orcid.org/0000-0002-9324-3946
NIKE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peptide receptor radionuclide therapy (PRRT) has been strengthened since the publication of NETTER-1. Nevertheless, the correct positioning in the therapeutic algorithm is debated, and no optimal sequence has yet been standardized. Possible criteria to predict the response to PRRT in neuroendocrine tumors (NET) have been proposed. The aim of this review is to define the perfect identity of the eligible patient who can mostly benefit from this therapy. Possible predictive criteria which have been analysed were: primary tumor site, grading, tumor burden, FDG PET and

Indexed as

Neuroendocrine TumorsOrganometallic CompoundsHumansOctreotidePositron Emission Tomography Computed TomographyPrognosisOctreotideOrganometallic CompoundsNeuroendocrine tumorsPeptide receptor radionuclide therapyPredictorResponseTherapeutic sequence

Identifiers

PMID32978685
PMCPMC8346456

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.