Evidence map›Paper›PMID 32978638›Full record

ArticleIrish journal of medical science2021

Sepsis in surgical inpatients: under-recognised but with significant consequences.

Aoife Reilly, Ali Basil Ali, Mairead Skally, Leah Gaughan, Vida Hamilton, Alexandra Troy, Hilary Humphreys, Deborah McNamara, Fidelma Fitzpatrick

Abstract read
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Article in Irish journal of medical science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 84% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Aoife ReillyDepartment of Clinical Microbiology, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland. areilly@rcsi.ie.ORCID http://orcid.org/0000-0002-3951-3845
Ali Basil AliDepartment of Clinical Microbiology, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland.
Mairead SkallyDepartment of Microbiology, Beaumont Hospital, Dublin 9, Ireland.
Leah GaughanDepartment of Pharmacy, Beaumont Hospital, Dublin 9, Ireland.
Vida HamiltonDepartment of Anaesthesia & Intensive Care, University College Hospital, Waterford, Ireland.
Alexandra TroyDepartment of Surgery, Beaumont Hospital, Dublin 9, Ireland.
Hilary HumphreysDepartment of Clinical Microbiology, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland.
Deborah McNamaraDepartment of Surgery, Beaumont Hospital, Dublin 9, Ireland.
Fidelma FitzpatrickDepartment of Clinical Microbiology, Royal College of Surgeons in Ireland (RCSI), Dublin 2, Ireland.
Beaumont Hospital · IERoyal College of Surgeons in Ireland · IEUniversity Hospital Waterford · IE

Funding

Irish Health Research Board SS-2018-068
6 · The paper itself

Abstract

backgroundThe true incidence of sepsis in surgical cohorts in Ireland remains unclear. According to inpatient audits, patients in surgical diagnostic groups (DRG) who developed sepsis had a longer length of stay and higher mortality rate compared with medical DRG patients who developed sepsis.

aimsWe investigated sepsis incidence on a general surgical ward to identify risk factors and strategies to improve management.

methodsDemographics, admission and discharge details, infection risk factors, infection, and sepsis were studied prospectively on a surgical ward in July 2018.

resultsThe mean age of 164 patients was 60.5 years (range 18-93 years), 107 (65.2%) were admitted electively, 16 (9.8%) were colonised with a multidrug-resistant organism (MDRO), and 30 (18.3%) were classified as frail on admission. Twelve (7.3%) developed sepsis (ward sepsis rate 118.2/10,000 bed days used). 'Sepsis' was documented in six cases and the national sepsis screening form used in four patients. Patients with sepsis were three times as likely to be MDRO-colonised (OR 3.56; 95% CI = 0.86-14.82; p = 0.065) or frail (OR 3.63; 95% CI = 1.07-12.35; p = 0.03), four times as likely to be an inpatient at the end of the study (OR 4.22, 96% CI 1.23-14.49; p = 0.01), and three times as likely to be readmitted (OR 3.46, 95% CI 1.02-11.76; p = 0.03).

conclusionSepsis was under-documented, and barriers exist with use of the national sepsis screening form. Frailty, which is a sepsis risk factor, should be assessed pre-operatively to maximise prevention.

Indexed as

AdolescentAdultAgedAged, 80 and overElective Surgical ProceduresFemaleHospitalizationHumansInpatientsMaleMiddle AgedProspective StudiesRisk FactorsSepsisYoung AdultFrailtyGeneral surgerySepsisSurgical inpatients

Identifiers

PMID32978638
OpenAlexW3089019566

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.