Evidence map›Paper›PMID 32978284›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2021

Repurposing

Amanda J Boyle, Junchao Tong, Sami S Zoghbi, Victor W Pike, Robert B Innis, Neil Vasdev

Open access · bronzeAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Repurposing [Molecular imaging and biology · 2022
    Article
  2. PET imaging of glycogen synthase kinase-3 in pancreatic cancer xenograft mouse models.American journal of nuclear medicine and molecular imaging · 2022
    Article
  3. Evaluation of a CD13 and Integrin αFrontiers in oncology · 2022
    Article
  4. Is cyclooxygenase-1 involved in neuroinflammation?Journal of neuroscience research · 2021
    Review
  5. Article
  6. Synthesis of [ACS chemical neuroscience · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 3 countries.

Amanda J BoyleAzrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Junchao TongAzrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada.
Sami S ZoghbiNational Institute of Mental Health, Bethesda, Maryland; and.
Victor W PikeNational Institute of Mental Health, Bethesda, Maryland; and.
Robert B InnisNational Institute of Mental Health, Bethesda, Maryland; and.
Neil VasdevAzrieli Centre for Neuro-Radiochemistry, Brain Health Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada neil.vasdev@utoronto.ca.
Centre for Addiction and Mental Health · CANational Institute of Mental Health · US

Funding

PET Radiopharmaceutical SciencesZIAMH002793 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI PIKE, VICTOR W · 2009 to 2025
$69.8M
Clinical Evaluation of PET RadiotracersZIAMH002852 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$48.6M
Translational Evaluation Of PET RadiotracersZIAMH002795 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI INNIS, ROBERT · 2009 to 2025
$32.0M
Intramural NIH HHS ZIA MH002793Intramural NIH HHS ZIA MH002795Intramural NIH HHS ZIA MH002852
6 · The paper itself

Abstract

Cyclooxygenase-1 (COX-1), a biomarker for neuroinflammation, is implicated in the progression and prognosis of ovarian cancer (OvCa). This study considered the repurposing of

Indexed as

Carbon RadioisotopesCell Transformation, NeoplasticDrug RepositioningPositron-Emission TomographyAnimalsCell Line, TumorCyclooxygenase 1FemaleHumansMiceOvarian NeoplasmsCarbon-11Carbon RadioisotopesCyclooxygenase 111C, COX-1cyclooxygenase-1ovarian cancerPETrepurposing

Identifiers

PMID32978284
PMCPMC8844262
OpenAlexW3089028593

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.