Evidence map›Paper›PMID 32977839›Full record

ArticleAlzheimer's research & therapy2020

Associations between social and intellectual activities with cognitive trajectories in Chinese middle-aged and older adults: a nationally representative cohort study.

Haibin Li, Changwei Li, Anxin Wang, Yanling Qi, Wei Feng, Chengbei Hou, Lixin Tao, Xiangtong Liu, Xia Li, Wei Wang and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Alzheimer's research & therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 71 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 1 pooled it
7.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 1 synthesis or guideline pooled it, 144 citations in OpenAlex.

  1. Pooled it
  2. Dynamic frailty exposure and cognitive aging trajectories: A multicohort study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
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  17. Psychosocial factors associated with perceived cognitive functioning in prostate cancer survivors: an exploratory cross-sectional analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
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11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Haibin LiDepartment of Epidemiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Changwei LiDepartment of Epidemiology, Tulane University School of Public Health and Tropical Medicine, 1440 Canal Street, New Orleans, Louisiana, 70112, USA. cli8@tulane.edu.
Anxin WangChina National Clinical Research Center for Neurological Diseases, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Yanling QiDepartment of Health Care Administration, College of Health and Human Services, California State University, Long Beach, 1250 Bellflower Blvd, Long Beach, CA, 90840, USA.
Wei FengDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, No. 10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China.
Chengbei HouCenter for Evidence-Based Medicine, Xuanwu Hospital, Capital Medical University, Beijing, China.
Lixin TaoDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, No. 10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China.
Xiangtong LiuDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, No. 10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China.
Xia LiDepartment of Mathematics and Statistics, La Trobe University, Melbourne, VIC, Australia.
Wei WangGlobal Health and Genomics, School of Medical Sciences and Health, Edith Cowan University, Perth, WA, 6027, Australia.
Deqiang ZhengDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, No. 10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China. dqzheng@ccmu.edu.cn.
Xiuhua GuoDepartment of Epidemiology and Health Statistics, School of Public Health, Capital Medical University, No. 10 Xitoutiao, You'anmen Wai, Fengtai District, Beijing, 100069, China. statguo@ccmu.edu.cn.ORCID 0000-0001-6657-6940
Capital Medical University · CNCalifornia State University, Long Beach · USEdith Cowan University · AUTulane University · US

Funding

Integrting Information About Aging SurveysR01AG030153 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Sara Adar, Alden L. Gross · 2007 to 2026
$41.7M
Mega Meta Data Set of the Health and Retirement Surveys Around the WorldRC2AG036619 · NIA · RAND CORPORATION · PI KAPTEYN, ARIE · 2009 to 2010
$2.0M
Archiving & Creating User Friendly Data: the Longitudinal Aging Survey in IndiaR03AG043052 · NIA · RAND CORPORATION · PI LEE, JINKOOK · 2012 to 2012
$95k
NIA NIH HHS R01 AG030153NIA NIH HHS R03 AG043052NIA NIH HHS RC2 AG036619
6 · The paper itself

Abstract

backgroundAssociations between the frequency of social and intellectual activities and cognitive trajectories are understudied in Chinese middle-aged and older adults. We aimed to examine this association in a nationally representative longitudinal study.

methodsThe China Health and Retirement Longitudinal Study (CHARLS) is a nationally representative sample of Chinese middle-aged and older participants. The frequency of social and intellectual activities was measured at baseline. Interview-based cognitive assessments of orientation and attention, episodic memory, and visuospatial skills and the calculation of combined global scores were assessed every 2 years from 2011 to 2016. Cognitive aging trajectories over time were analyzed using group-based trajectory modeling, and the associations of the trajectory memberships with social and intellectual activities were analyzed using multinomial logistic regression. Odds ratios (OR) and 95% confidence intervals (CI) were reported.

resultsAmong 8204 participants aged 50-75 years at baseline, trajectory analysis identified three longitudinal patterns of cognitive function based on the global cognitive scores: "persistently low trajectory" (n = 1550, 18.9%), "persistently moderate trajectory" (n = 3194, 38.9%), and "persistently high trajectory" (n = 3460, 42.2%). After adjustment for sociodemographic variables, lifestyles, geriatric symptoms, and health conditions, more frequent intellectual activities (OR 0.54, 95% CI 0.38-0.77) and social activities (OR 0.79, 95% CI 0.65-0.95) were both associated with a lower likelihood of being in the "persistently low trajectory" for global cognitive function.

conclusionsThese findings suggested that more frequent social and intellectual activities were associated with more favorable cognitive aging trajectories.

Indexed as

AgingCognitionAgedChinaCohort StudiesHumansLogistic ModelsLongitudinal StudiesMiddle AgedAgingCognitive trajectoryGroup-based trajectory modelsIntellectual activityLongitudinal studySocial activity

Identifiers

PMID32977839
PMCPMC7519540
OpenAlexW3096162977

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.