Evidence map›Paper›PMID 32977822›Full record

ArticleRadiation oncology (London, England)2020

p63

Hongming Huang, Kai Sen Tan, Suizi Zhou, Tian Yuan, Jing Liu, Hsiao Hui Ong, Qianmin Chen, Junxiao Gao, Minghong Xu, Zhenchao Zhu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Radiation oncology (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. [Analysis of influencing factors on secondary olfactory dysfunction in different types of chronic sinusitis].Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology head and neck surgery · 2025
    Article
  5. Article
  6. Article
  7. Radiation-induced rhinosinusitis: Mechanism research and clinical progress review.World journal of otorhinolaryngology - head and neck surgery · 2024
    Review
  8. Review
  9. Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 2 countries.

Hongming HuangDepartment of Otolaryngology, Guangdong Provincial People's Hospital and Guangdong Academy of Medical Sciences, Guangzhou, China.ORCID http://orcid.org/0000-0003-1875-9798
Kai Sen TanDepartment of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.
Suizi ZhouDepartment of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.
Tian YuanDepartment of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.
Jing LiuDepartment of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.
Hsiao Hui OngDepartment of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.
Qianmin ChenDepartment of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore.
Junxiao GaoDepartment of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Minghong XuDepartment of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Zhenchao ZhuDepartment of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China.
Qianhui QiuDepartment of Otolaryngology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, China. qiuqianhui@hotmail.com.
De Yun WangDepartment of Otolaryngology, National University of Singapore, 1E Kent Ridge Rd, Singapore, 119228, Singapore. entwdy@nus.edu.sg.
National University of Singapore · SGZhujiang Hospital · CNSun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSquamous metaplasia (SM) is an irreversible form of airway epithelial remodeling. Hyperproliferation of basal cells was observed in squamous metaplastic epithelium of chronically inflamed airway. However, the association of such aberrant proliferation of basal cells with SM in the nasal epithelium after radiation damage remains unclear. The aim of this study was to investigate SM and accompanying levels of p63

methodsWe assessed the prevalence of SM and the expression of p63

resultsThe prevalence of SM and the number of p63

conclusionSM is increased in the nasal epithelium of patients with CRSr, in which aberrant levels of p63

Indexed as

AdultAgedBasal Cell CarcinomaCarcinoma, Squamous CellCase-Control StudiesChronic DiseaseFemaleHumansKeratin-5MaleMetaplasiaMiddle AgedNasal MucosaPrognosisRadiotherapyRhinitisKeratin-5KRT5 protein, humanTP63 protein, humanTranscription FactorsTumor Suppressor ProteinsBasal cellsChronic Rhinosinusitis(CRS)EpitheliumRadiationSquamous metaplasia

Identifiers

PMID32977822
PMCPMC7517817
OpenAlexW3087923884

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.