Evidence map›Paper›PMID 32977783›Full record

ArticleBMC musculoskeletal disorders2020

Association between device-measured physical activity and lumbar Modic changes.

Marella Modarress Julin, Jesperi Saukkonen, Petteri Oura, Maisa Niemelä, Juho-Antti Junno, Juhani Määttä, Jaakko Niinimäki, Timo Jämsä, Raija Korpelainen, Jaro Karppinen

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. A cross-sectional association study of paravertebral muscle quality and modic changes in patients with chronic nonspecific low back pain.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2025
    Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Marella Modarress JulinMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland. marella.julin@oulu.fi.
Jesperi SaukkonenMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.
Petteri OuraMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.
Maisa NiemeläMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.
Juho-Antti JunnoCenter for Life Course Health Research, PO Box 5000, FI-90014, Oulu, Finland.
Juhani MäättäMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.
Jaakko NiinimäkiMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.
Timo JämsäMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.
Raija KorpelainenMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.
Jaro KarppinenMedical Research Center Oulu, Oulu University Hospital and University of Oulu, PO Box 5000, FI-90014, Oulu, Finland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundModic changes (MC) in the lumbar spine are considered one potential etiological factor behind low back pain (LBP). Multiple risk factors for MC have been suggested, including male gender, smoking and factors affecting hyperloading and mechanical stress such as high body mass index (BMI), strenuous physical work and high occupational and leisure-time physical activity (PA). So far, the effect of PA on the occurrence of MC has remained under debate due to contradictory findings. The purpose of this study was to investigate the possible association between device-measured moderate-to-vigorous PA (MVPA) (≥ 3.5 METs) and lumbar MC.

methodsThe study had 1374 participants from the Northern Finland Birth Cohort 1966. At the age of 46-48, PA was measured by a wrist-worn accelerometer, and lumbar magnetic resonance imaging (MRI) was carried out to determine MC. We analyzed the association between Type 1 (MC1) and Type 2 (MC2) MC and daily amount of MVPA (min/day) using sex-stratified logistic regression models before and after adjustment for BMI, socioeconomic status, smoking, and accelerometer wear time.

resultsAmong men, increased amount of MVPA was positively associated with any MC (adjusted OR corresponding to every 60 min/day of MVPA 1.41; 95% confidence interval (CI) 1.01 to 1.95) and MC2 (OR 1.54; 95% CI 1.14 to 2.08), but not with MC1 (OR 1.06; 95% CI 0.80 to 1.39). Among women, we only found a positive association between MVPA and MC1 before adjustments (unadjusted OR 1.42; 95% CI 1.06 to 1.92).

conclusionAmong men, increased amount of MVPA was associated with increased odds of any MC and particularly MC2. Among women, MVPA was not independently associated with MC.

Indexed as

Low Back PainLumbosacral RegionExerciseFemaleFinlandHumansLumbar VertebraeMaleCohort studyDevice-based measurementsLumbar MRILumbar spineModic changesMVPAPhysical activitySkeletal healthVertebrae

Identifiers

PMID32977783
PMCPMC7519485

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.