Observational studyBMC pregnancy and childbirth2020
Prelabour caesarean section and neurodevelopmental outcome at 4 and 12 months of age: an observational study.
Observational study in BMC pregnancy and childbirth, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Effects of vaginal microbiota transfer on social-emotional and neurodevelopment in cesarean-born infants: 12-month follow-up of a pilot randomized clinical trial.Acta obstetricia et gynecologica Scandinavica · 2026Trial
- Effectiveness of a training program for the acquisition of motor milestones in infants: a randomized clinical trial.Italian journal of pediatrics · 2025Trial
- Caesarean section may be associated with suspected motor developmental delay at 3 years of age in the Japan Environment and Children's Study.Scientific reports · 2026Article
- Epidural-Related Maternal Fever Is Associated With Structural Alterations in Vaginal Floral Homeostasis Among Parturients.Obstetrics and gynecology international · 2026Article
- Impact of Delivery Method on Initiation and Continuation of Breastfeeding: A Prospective Cohort Study.Children (Basel, Switzerland) · 2025Article
- Health outcomes up to 5 years in children born as a second child after a previous caesarean section in a first pregnancy: a Swedish population-based register study between 1999 and 2015.BMJ paediatrics open · 2025Article
- Mode of delivery and behavioral and neuropsychological outcomes in children at 10 years of age.Journal of perinatal medicine · 2024Article
- Cesarean birth is associated with lower motor and language development scores during early childhood: a longitudinal analysis of two cohorts.Scientific reports · 2024Article
- Maternal and neonatal blood vitamin D status and neurodevelopment at 24 months of age: a prospective birth cohort study.World journal of pediatrics : WJP · 2023Article
- Association of perinatal factors with suspected developmental delay in urban children aged 1-36 months - a large-scale cross-sectional study in China.BMC pediatrics · 2023Article
- Early motor development: risk factors for delay in a population study in Southern Brazil.Revista de saude publica · 2023Article
- Article
- The association of cesarean section with overweight and neurodevelopment of Chinese children aged 1-5 months.Frontiers in pediatrics · 2022Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWith prelabour caesarean section rates growing globally, there is direct and indirect evidence of negative cognitive outcomes in childhood. The objective of this study was to assess the short-term neurodevelopmental outcomes after prelabour caesarean section as compared to vaginally born infants.
methodsWe conducted a prospective, observational study of infants delivered by prelabour caesarean section at the Hospital of Halland, Halmstad, Sweden and compared their development with an historical group of infants born by non-instrumental vaginal delivery.
resultsInfants born by prelabour caesarean section were compared with a group of vaginally born infants. Follow-up assessments were performed at 4 and 12 months. Prelabour caesarean infants (n = 66) had significantly lower Ages and Stages Questionnaire, second edition (ASQ-II) scores in all domains (communication, gross motor, fine motor, problem solving and personal-social) at 4 months of age with an adjusted mean difference (95% CI) of - 20.7 (- 28.7 to - 12.6) in ASQ-II total score as compared to vaginally born infants (n = 352). These differences remained for gross-motor skills at the 12 month assessment, adjusted mean difference (95% CI) -4.7 (- 8.8 to - 0.7), n = 62 and 336.
conclusionsAdverse neurodevelopmental outcomes in infants born by prelabour caesarean section may be apparent already a few months after birth. Additional studies are warranted to explore this relationship further.
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