ArticleViruses2020
A Sporadic and Lethal Lassa Fever Case in Forest Guinea, 2019.
Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Clinical characterization of Lassa fever: A systematic review of clinical reports and research to inform clinical trial design.PLoS neglected tropical diseases · 2021Pooled it
- Adaptive Design for Phase II/III Platform Trial of Lassa Fever Therapeutics.Emerging infectious diseases · 2025Trial
- Strengthening diagnostic capacity for viral hemorrhagic fevers in Forest Guinea: advances in Lassa fever case detection.Npj viruses · 2026Article
- Nosocomial Outbreak of Lassa Fever in Conakry, Guinea, 2022.The Journal of infectious diseases · 2026Article
- Genomic Surveillance of Lassa Virus through In-Country Sequencing, Guinea.Emerging infectious diseases · 2026Article
- Serosurveillance Identifies an Endemic Hotspot of Lassa Fever in Faranah, Upper Guinea.The Journal of infectious diseases · 2025Article
- Whole-genome sequencing of Lassa virus from dry blood spots: a comparative evaluation.Infectious diseases of poverty · 2025Article
- Rapid response to hemorrhagic fever emergence in Guinea: community-based systems can enhance engagement and sustainability.PloS one · 2025Article
- Spatio-temporal spread of Lassa virus and a new rodent host in the Mano River Union area, West Africa.Emerging microbes & infections · 2024Article
- How has Guinea learnt from the response to outbreaks? A learning health system analysis.BMJ global health · 2023Article
- The West Africa Lassa fever Consortium pre-positioned protocol for a Phase II/III adaptive, randomised, controlled, platform trial to evaluate multiple Lassa fever therapeutics.Wellcome open research · 2023Article
- Article
- Detection of Lassa virus in wild rodent feces: Implications for Lassa fever burden within households in the endemic region of Faranah, Guinea.One health (Amsterdam, Netherlands) · 2021Article
- Guinea's response to syndemic hotspots.BMJ global health · 2021Article
Corrections and comments
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Authors and funding
12 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Lassa fever is a rodent-borne disease caused by Lassa virus (LASV). It causes fever, dizziness, vertigo, fatigue, coughing, diarrhea, internal bleeding and facial edema. The disease has been known in Guinea since 1960 but only anectodical acute cases have been reported to date. In January 2019, a 35-year-old man, a wood merchant from Kissidougou, Forest Guinea, presented himself at several health centers with persistent fever, frequent vomiting and joint pain. He was repeatedly treated for severe malaria, and died three weeks later in Mamou regional hospital. Differential diagnosis identified LASV as the cause of death. No secondary cases were reported. The complete LASV genome was obtained using next-generation sequencing. Phylogenetic analysis showed that this strain, namely the Kissidougou strain, belongs to the clade IV circulating in Guinea and Sierra Leone, and is thought to have emerged some 150 years ago. Due to the similarity of symptoms with malaria, Lassa fever is still a disease that is difficult to recognize and that may remain undiagnosed in health centers in Guinea.
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