Evidence map›Paper›PMID 32977607›Full record

ArticleToxins2020

Bee Venom Phospholipase A2 Ameliorates Atherosclerosis by Modulating Regulatory T Cells.

Geun-Hyung Kang, Sujin Lee, Da Bin Choi, Dasom Shin, Jahee Kim, HyeJin Yang, Hyunsu Bae

Open access · goldAbstract read
In one paragraph

Article in Toxins, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Therapeutic Bioactivity Exerted by theMolecules (Basel, Switzerland) · 2025
    Article
  4. Review
  5. A Spotlight on the Egyptian Honeybee (Animals : an open access journal from MDPI · 2022
    Review
  6. Review
  7. Review
  8. Bee venom ameliorates cardiac dysfunction in diabetic hyperlipidemic rats.Experimental biology and medicine (Maywood, N.J.) · 2021
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Geun-Hyung KangDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdamoon-gu, Seoul 02453, Korea.ORCID 0000-0001-6803-8396
Sujin LeeDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdamoon-gu, Seoul 02453, Korea.
Da Bin ChoiDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdamoon-gu, Seoul 02453, Korea.
Dasom ShinDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdamoon-gu, Seoul 02453, Korea.ORCID 0000-0002-8699-0169
Jahee KimDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdamoon-gu, Seoul 02453, Korea.
HyeJin YangDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdamoon-gu, Seoul 02453, Korea.
Hyunsu BaeDepartment of Physiology, College of Korean Medicine, Kyung Hee University, 26-6 Kyungheedae-ro, Dongdamoon-gu, Seoul 02453, Korea.ORCID 0000-0002-0299-3582
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Atherosclerosis is a chronic inflammatory disease caused by lipids and calcareous accumulations in the vascular wall due to an inflammatory reaction. Recent reports have demonstrated that regulatory T (Treg) cells have an important role as a new treatment for atherosclerosis. This study suggests that bee venom phospholipase A2 (bvPLA2) may be a potential therapeutic agent in atherosclerosis by inducing Treg cells. We examined the effects of bvPLA2 on atherosclerosis using

Indexed as

AnimalsAortaAortic DiseasesAtherosclerosisBee VenomsCytokinesDiet, High-FatDisease Models, AnimalFoam CellsForkhead Transcription FactorsInsect ProteinsLipid MetabolismMaleMice, Inbred C57BLMice, Knockout, ApoEPhospholipases A2Bee VenomsCytokinesForkhead Transcription FactorsFoxp3 protein, mouseInsect ProteinsPhospholipases A2atherosclerosisbee venomphospholipase A2PLA2Tregs

Identifiers

PMID32977607
PMCPMC7598180
OpenAlexW3089102936

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.