Evidence map›Paper›PMID 32977582›Full record

ArticleCancers2020

Transcriptomics-Based Drug Repurposing Approach Identifies Novel Drugs against Sorafenib-Resistant Hepatocellular Carcinoma.

Kelly Regan-Fendt, Ding Li, Ryan Reyes, Lianbo Yu, Nissar A Wani, Peng Hu, Samson T Jacob, Kalpana Ghoshal, Philip R O Payne, Tasneem Motiwala

Open access · goldAbstract read
In one paragraph

Article in Cancers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 73 citations in OpenAlex.

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  15. International journal of medical sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Kelly Regan-FendtDepartment of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Ding LiDepartment of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Ryan ReyesDepartment of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Lianbo YuDepartment of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Nissar A WaniDepartment of Biotechnology, School of Life Sciences, Central University of Kashmir, Ganderbal, Jammu and Kashmir 191201, India.
Peng HuDepartment of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Samson T JacobDepartment of Cancer Biology and Genetics, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Kalpana GhoshalDepartment of Pathology, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
Philip R O PayneWashington University Institute for Informatics, Washington University in St. Louis School of Medicine, St. Louis, MO 63108, USA.
Tasneem MotiwalaDepartment of Biomedical Informatics, The Ohio State University College of Medicine, Columbus, OH 43210, USA.
The Ohio State University · USCentral University of Kashmir · INWashington University in St. Louis · US

Funding

MOLECULAR MECHANISMS OF DIET-INDUCED CARCINOGENESISR01CA086978 · NCI · OHIO STATE UNIVERSITY · PI GHOSHAL, KALPANA, JACOB, SAMSON T · 2002 to 2018
$4.9M
Role of microR-122 in Hepatocarcinogenesis using Conditional Knockout MiceR01CA193244 · NCI · OHIO STATE UNIVERSITY · PI GHOSHAL, KALPANA · 2015 to 2019
$2.3M
NCI NIH HHS CA086978NCI NIH HHS CA193244NCI NIH HHS R01 CA086978NCI NIH HHS R01 CA193244The Ohio State University Comprehensive Cancer Center Pelotonia Idea GrantU.S. National Library of Medicine T15LM0112750
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dasatinibdrug repurposingdrug resistancefostamatinibhepatocellular carcinomasorafenib

Identifiers

PMID32977582
PMCPMC7598246
OpenAlexW3089333769

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.