Evidence map›Paper›PMID 32977395›Full record

ArticleNutrients2020

Physiologic Effects of Exogenous Dextrose in Murine

Byron Chuan, Lanping Guo, Bryce Cooper, Sagar Rawal, Teresa Gallego-Martin, Yingze Zhang, Bryan J McVerry, Christopher P O'Donnell, Faraaz Ali Shah

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Byron ChuanDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Lanping GuoDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Bryce CooperDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Sagar RawalDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Teresa Gallego-MartinDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Yingze ZhangDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.ORCID 0000-0001-6947-2901
Bryan J McVerryDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Christopher P O'DonnellDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
Faraaz Ali ShahDivision of Pulmonary, Allergy, Critical Care Medicine, University of Pittsburgh, Pittsburgh, PA 15261, USA.
University of Pittsburgh · US

Funding

Metabolic Effects of Early Nutritional Support in Sepsis: A Translational InvestigationK23GM122069 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI SHAH, FARAAZ ALI · 2016 to 2020
$764k
NIGMS NIH HHS K23 GM122069NIH HHS 5K23GM122069
6 · The paper itself

Abstract

Sepsis is characterized by a dysregulated immune response to infection. Nutrition is important in the care of septic patients, but the effects of specific nutrients on inflammation in sepsis are not well defined. Our prior work has shown benefits from early enteral dextrose infusion in a preclinical endotoxemia model of sepsis. In the current study, we extend our initial work to examine the effects of dextrose infusions, varying by route of administration, on inflammation and glycemic control in a more clinically relevant and translational model of

Indexed as

AnimalsDisease Models, AnimalGlucoseGlycemic ControlHyperglycemiaInflammationKlebsiella pneumoniaeLung InjuryMaleMiceMice, Inbred C57BLPneumoniaProtective AgentsSepsisGlucoseProtective Agentscarbohydratehyperglycemiainflammationpneumoniasepsis

Identifiers

PMID32977395
PMCPMC7597955
OpenAlexW3088566794

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.