Evidence map›Paper›PMID 32977358›Full record

ArticleBrain and behavior2020

Peripheral versus central mechanisms of the cannabinoid type 2 receptor agonist AM1710 in a mouse model of neuropathic pain.

Jenny L Wilkerson, Lauren B Alberti, Audra A Kerwin, Catherine A Ledent, Ganesh A Thakur, Alexandros Makriyannis, Erin D Milligan

Open access · goldAbstract read
In one paragraph

Article in Brain and behavior, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Cannabinoid CBBritish journal of pharmacology · 2025
    Review
  2. Article
  3. Article
  4. Emerging role of macrophages in neuropathic pain.Journal of orthopaedic translation · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. The role of protein kinases in diabetic neuropathic pain: an update review.Journal of diabetes and metabolic disorders · 2023
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Jenny L WilkersonDepartment of Neurosciences, Health Sciences Center, School of Medicine, University of New Mexico, Albuquerque, NM, USA.ORCID 0000-0002-5594-061X
Lauren B AlbertiDepartment of Neurosciences, Health Sciences Center, School of Medicine, University of New Mexico, Albuquerque, NM, USA.
Audra A KerwinDepartment of Neurosciences, Health Sciences Center, School of Medicine, University of New Mexico, Albuquerque, NM, USA.
Catherine A LedentUniversite libre de Bruxelles, Brussels, Belgium.
Ganesh A ThakurCenter for Drug Discovery, Northeastern University, Boston, MA, USA.
Alexandros MakriyannisCenter for Drug Discovery, Northeastern University, Boston, MA, USA.
Erin D MilliganDepartment of Neurosciences, Health Sciences Center, School of Medicine, University of New Mexico, Albuquerque, NM, USA.
University of New Mexico · USNortheastern University · USUniversité Libre de Bruxelles · BE

Funding

Spinal Neuroimmune Mechanisms Underlying IL-10 Gene Therapy for Pain ControlR01DA018156 · NIDA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MILLIGAN, ERIN DAMITA · 2004 to 2014
$3.3M
Prenatal Alcohol Exposure Potentiates Pain via Lifelong Spinal-immune ChangesR01AA025967 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI MILLIGAN, ERIN DAMITA · 2017 to 2021
$1.5M
NIAAA NIH HHS R01 AA025967NIDA NIH HHS R01 DA018156
6 · The paper itself

Abstract

The CB

Indexed as

CannabinoidsNeuralgiaAnimalsCannabinoid Receptor AgonistsChromonesHyperalgesiaMiceSpinal Cord3-(1,1-dimethyl-heptyl)-1-hydroxy-9-methoxy-benzo(c)chromen-6-oneCannabinoid Receptor AgonistsCannabinoidsChromonescannabinoidMCP-1/CCL-2mouseparaffin immunohistochemistryspectral analysis

Identifiers

PMID32977358
PMCPMC7749576
OpenAlexW3088846504

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.