Evidence map›Paper›PMID 32976991›Full record

ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2020

Temporal and age distributions of SARS-CoV-2 and other coronaviruses, southeastern France.

Philippe Colson, Vera Esteves-Vieira, Audrey Giraud-Gatineau, Christine Zandotti, Véronique Filosa, Hervé Chaudet, Jean-Christophe Lagier, Didier Raoult

Open access · goldAbstract read
In one paragraph

Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Emergence and outcomes of the SARS-CoV-2 'Marseille-4' variant.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Philippe ColsonIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France; Aix-Marseille Univ., Microbes Evolution Phylogeny and Infections (MEPHI), Institut de recherche pour le développement (IRD), Marseille, France.
Vera Esteves-VieiraIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France.
Audrey Giraud-GatineauIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France; Aix-Marseille Univ., Microbes Evolution Phylogeny and Infections (MEPHI), Institut de recherche pour le développement (IRD), Marseille, France; Service de Santé des Armées (SSA), Marseille, France.
Christine ZandottiIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France.
Véronique FilosaIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France.
Hervé ChaudetIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France; Aix-Marseille Univ., Microbes Evolution Phylogeny and Infections (MEPHI), Institut de recherche pour le développement (IRD), Marseille, France; Service de Santé des Armées (SSA), Marseille, France.
Jean-Christophe LagierIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France; Aix-Marseille Univ., Microbes Evolution Phylogeny and Infections (MEPHI), Institut de recherche pour le développement (IRD), Marseille, France.
Didier RaoultIHU Méditerranée Infection, Marseille, France; Assistance Publique-Hôpitaux de Marseille (AP-HM), Marseille, France; Aix-Marseille Univ., Microbes Evolution Phylogeny and Infections (MEPHI), Institut de recherche pour le développement (IRD), Marseille, France. Electronic address: didier.raoult@gmail.com.
Méditerranée Infection Foundation · FRHôpital de la Timone · FRAssistance Publique Hôpitaux de Marseille · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe SARS-CoV-2 epidemic presents a poorly understood epidemiological cycle. We aimed to compare the age and weekly distributions of the five human coronaviruses, including SARS-CoV-2, that circulated in southeastern France.

methodsWe analyzed all available diagnoses of respiratory viruses, including SARS-CoV-2, performed between 09/2013 and 05/2020 at the University Hospital Institute Méditerranée Infection in Marseille, southeastern France.

resultsFor SARS-CoV-2, positive children <15 years of age represented 3.4% (228/6,735) of all positive cases, which is significantly less than for endemic coronaviruses (46.1%; 533/1,156; p < 0.001). Among 10,026 patients tested for SARS-CoV-2 and endemic coronaviruses in 2020, children <15 years represented a significantly lower proportion of all positive cases for SARS-CoV-2 than for endemic coronaviruses [2.2% (24/1,067) vs. 33.5% (149/445), respectively; p < 0.001]. Epidemic curves for endemic coronaviruses and SARS-CoV-2 in 91,722 patients showed comparable bell-shaped distributions with a slight time lag. In contrast, the age distribution of endemic coronaviruses and 14 other respiratory viruses differed significantly compared to that of SARS-CoV-2, which was the only virus to relatively spare children.

conclusionsWe observed for SARS-CoV-2 a temporal distribution resembling that of endemic coronaviruses but an age distribution that relatively spares the youngest subjects, who are those the most exposed to endemic coronaviruses.

Indexed as

AdolescentAdultAgedAged, 80 and overAge DistributionChildChild, PreschoolCoronavirusFranceHumansInfantInfant, NewbornMiddle AgedSARS-CoV-2Young AdultAgeChildrenCross-immunityEndemic coronavirusSARS-CoV-2Southeastern France

Identifiers

PMID32976991
PMCPMC7511210
OpenAlexW3089176402

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.