Evidence map›Paper›PMID 32976703›Full record

ArticleAmerican journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2021

Preexisting melanoma and hematological malignancies, prognosis, and timing to solid organ transplantation: A consensus expert opinion statement.

David P Al-Adra, Laura Hammel, John Roberts, E Steve Woodle, Deborah Levine, Didier Mandelbrot, Elizabeth Verna, Jayme Locke, Jonathan D'Cunha, Maryjane Farr and 25 more

Open access · hybridAbstract readConsensus Statement
In one paragraph

Article in American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
3.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 83 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Kidney disease and transplantation in childhood cancer survivors.Pediatric nephrology (Berlin, Germany) · 2026
    Review
  4. Article
  5. Observational
  6. Skin Cancer in Solid Organ Transplant Recipients: A Review.American journal of clinical dermatology · 2026
    Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Article
  13. Cure models, survival probabilities, and solid organ transplantation for patients with colorectal cancer.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2025
    Article
  14. Review
  15. Review
  16. Article
  17. Outcomes in solid organ transplant recipients with a pretransplant diagnosis of melanoma.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2024
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

35 authors at 20 institutions in 2 countries.

David P Al-AdraDepartment of Surgery, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0002-4469-6375
Laura HammelDepartment of Anesthesiology, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin.
John RobertsDepartment of Surgery, University of California San Francisco, San Francisco, California.
E Steve WoodleDepartment of Surgery, University of Cincinnati, Cincinnati, Ohio.ORCID 0000-0003-4280-0842
Deborah LevineDepartment of Medicine, University of Texas Health San Antonio, San Antonio, Texas.ORCID 0000-0002-2021-2233
Didier MandelbrotDepartment of Medicine, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin.
Elizabeth VernaDepartment of Medicine, New York-Presbyterian/Columbia, New York, New York.ORCID 0000-0002-9658-3751
Jayme LockeDepartment of Surgery, University of Alabama at Birmingham, Birmingham, Alabama.ORCID 0000-0002-0220-8716
Jonathan D'CunhaDepartment of Surgery, Mayo Clinic, Phoenix, Arizona, USA.
Maryjane FarrDepartment of Medicine, New York-Presbyterian/Columbia, New York, New York.
Deirdre SawinskiDepartment of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.ORCID 0000-0001-7903-8295
Piyush K AgarwalDepartment of Urology, University of Chicago, Chicago, Illinois.
Jennifer PlichtaDepartment of Surgery, Duke University School of Medicine, Durham, North Carolina.
Sandhya PruthiDepartment of Medicine, Mayo Clinic, Rochester, Minnesota.
Deborah FarrDepartment of Surgery, University of Texas Southwestern Medical Center, Dallas, Texas.
Richard CarvajalDepartment of Medicine, New York-Presbyterian/Columbia, New York, New York.
John WalkerDepartment of Medicine, University of Alberta, Edmonton, Alberta, Canada.
Fiona ZwaldPiedmont Transplant Institute, Piedmont Atlanta Hospital, Atlanta, Georgia.ORCID 0000-0001-9703-647X
Thomas HabermannHematology Division, Mayo Clinic, Rochester, Minnesota, USA.
Morie GertzHematology Division, Mayo Clinic, Rochester, Minnesota, USA.
Philip BiermanDepartment of Medicine, University of Nebraska Medical Center, Omaha, Nebraska.
Don S DizonLifespan Cancer Institute and Brown University, Providence, Rhode Island.
Carrie LangstraatDepartments of Obstetrics and Gynecology, Mayo Clinic, Rochester, Minnesota.
Talal Al-QaoudDepartment of Surgery, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin.ORCID 0000-0002-5215-6408
Scott EggenerDepartment of Urology, University of Chicago, Chicago, Illinois.
John P RichgelsDepartment of Urology, University of Chicago, Chicago, Illinois.
George J ChangDepartment of Surgical Oncology, The University of Texas, MD Anderson Cancer Center, Houston, Texas.
Cristina GeltzeilerDepartment of Surgery, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin.
Gonzalo SapisochinDepartment of Surgery, University of Toronto, Toronto, Ontario, Canada.
Rocco RicciardiDepartment of Surgery, Massachusetts General Hospital, Boston, Massachusetts.
Alexander S KrupnickDepartment of Surgery, University of Virginia, Charlottesville, Virginia.ORCID 0000-0002-1790-6197
Cassie KennedyDepartment of Medicine, Mayo Clinic, Rochester, Minnesota.
Nisha MohindraDepartment of Medicine, Northwestern University, Chicago, Illinois.
David P FoleyDepartment of Surgery, University of Wisconsin, School of Medicine and Public Health, Madison, Wisconsin.
Kymberly D WattDepartment of Medicine, Mayo Clinic, Rochester, Minnesota.ORCID 0000-0003-1776-3680
Mayo Clinic · USUniversity of Wisconsin–Madison · USPresbyterian Hospital · USUniversity of Chicago · USBrown University · USDuke University · USMassachusetts General Hospital · USNorthwestern University · USPiedmont Atlanta Hospital · USThe University of Texas Health Science Center at San Antonio · USThe University of Texas MD Anderson Cancer Center · USThe University of Texas Southwestern Medical Center · USUniversity of Alabama at Birmingham · USUniversity of Alberta · CAUniversity of California, San Francisco · USUniversity of Cincinnati · USUniversity of Nebraska Medical Center · USUniversity of Pennsylvania · USUniversity of Toronto · CAUniversity of Virginia · US

Funding

The Role of Neutrophils in Regulating Lung Transplant ToleranceP01AI116501 · NIAID · WASHINGTON UNIVERSITY · PI Andrew Eric Gelman · 2015 to 2026
$19.4M
The Role of Eosinophils in the Lung AllograftR01AI145108 · NIAID · UNIVERSITY OF VIRGINIA · PI Elizabeth A Jacobsen, ALEXANDER S. KRUPNICK · 2019 to 2026
$4.1M
BLRD VA I01 BX002299NIAID NIH HHS P01 AI116501NIAID NIH HHS R01 AI145108
6 · The paper itself

Abstract

Patients undergoing evaluation for solid organ transplantation (SOT) frequently have a history of malignancy. Only patients with treated cancer are considered for SOT but the benefits of transplantation need to be balanced against the risk of tumor recurrence, taking into consideration the potential effects of immunosuppression. Prior guidelines on timing to transplant in patients with a prior treated malignancy do not account for current staging, disease biology, or advances in cancer treatments. To update these recommendations, the American Society of Transplantation (AST) facilitated a consensus workshop to comprehensively review contemporary literature regarding cancer therapies, cancer stage specific prognosis, the kinetics of cancer recurrence, as well as the limited data on the effects of immunosuppression on cancer-specific outcomes. This document contains prognosis, treatment, and transplant recommendations for melanoma and hematological malignancies. Given the limited data regarding the risk of cancer recurrence in transplant recipients, the goal of the AST-sponsored conference and the consensus documents produced are to provide expert opinion recommendations that help in the evaluation of patients with a history of a pretransplant malignancy for transplant candidacy.

Indexed as

Hematologic NeoplasmsMelanomaOrgan TransplantationHumansNeoplasm Recurrence, LocalPrognosiscancer/malignancy/neoplasiaclinical research/practiceeditorial/personal viewpointorgan transplantation in generalpatient safetyrecipient selection

Identifiers

PMID32976703
PMCPMC8555431
OpenAlexW3088422310

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.