Evidence map›Paper›PMID 32976661›Full record

ArticleCancer science2020

Upregulation of S100A10 in metastasized breast cancer stem cells.

Hisano Yanagi, Takashi Watanabe, Tatsunori Nishimura, Takanori Hayashi, Seishi Kono, Hitomi Tsuchida, Munetsugu Hirata, Yuko Kijima, Shintaro Takao, Seiji Okada and 6 more

Open access · goldAbstract read
In one paragraph

Article in Cancer science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 27 citations in OpenAlex.

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  14. Prognostic Value of S100 Family mRNA Expression in Hepatocellular Carcinoma.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2024
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

Hisano YanagiDepartment of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.
Takashi WatanabeDepartment of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.
Tatsunori NishimuraDivision of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.
Takanori HayashiDepartment of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.
Seishi KonoDivision of Breast and Endocrine Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Hitomi TsuchidaDivision of Molecular and Cellular Biology, Kobe University Graduate School of Medicine, Kobe, Japan.
Munetsugu HirataDepartment of Breast Surgery, Fujita Health University School of Medicine, Toyoake, Japan.
Yuko KijimaDepartment of Breast Surgery, Fujita Health University School of Medicine, Toyoake, Japan.
Shintaro TakaoDivision of Breast and Endocrine Surgery, Kobe University Graduate School of Medicine, Kobe, Japan.
Seiji OkadaDivision of Hematopoiesis, Joint Research Center for Human Retrovirus Infection, Kumamoto University, Kumamoto, Japan.
Motoshi SuzukiDepartment of Molecular Oncology, Fujita Health University School of Medicine, Toyoake, Japan.
Kazuyoshi ImaizumiDepartment of Respiratory Medicine, Fujita Health University School of Medicine, Fujita Health University School of Medicine, Toyoake, Japan.
Kenji KawadaDepartment of Medical Oncology, Fujita Health University School of Medicine, Toyoake, Japan.
Hironobu MinamiDivision of Medical Oncology/Hematology, Kobe University Graduate School of Medicine, Kobe, Japan.ORCID https://orcid.org/0000-0001-8630-9145
Noriko GotohDivision of Cancer Cell Biology, Cancer Research Institute, Kanazawa University, Kanazawa, Japan.ORCID https://orcid.org/0000-0003-3733-260X
Yohei ShimonoDepartment of Biochemistry, Fujita Health University School of Medicine, Toyoake, Japan.ORCID https://orcid.org/0000-0002-6256-4704
Fujita Health University · JPKobe University · JPKanazawa University · JPKumamoto University · JP

Funding

Cancer Research Institute of Kanazawa UniversityFujita Health UniversityJapan Society for the Promotion of Science 15K14381Japan Society for the Promotion of Science 18K07231 : 19K23900: 20K07600Princess Takamatsu Cancer Research FundPromotion and Mutual Aid Corporation for Private Schools of Japan
6 · The paper itself

Abstract

Metastatic progression remains the major cause of death in human breast cancer. Cancer cells with cancer stem cell (CSC) properties drive initiation and growth of metastases at distant sites. We have previously established the breast cancer patient-derived tumor xenograft (PDX) mouse model in which CSC marker CD44

Indexed as

Up-RegulationAnimalsAnnexin A2Breast NeoplasmsCell Line, TumorDisease ProgressionFemaleGene Expression ProfilingGene Knockout TechniquesHumansHyaluronan ReceptorsLentivirusLiver NeoplasmsMatrix MetalloproteinasesMiceNeoplasm InvasivenessAnnexin A2CD44 protein, humanHyaluronan ReceptorsMatrix MetalloproteinasesS100 Calcium Binding Protein A10S100 Proteinsbreast cancercancer stem cellsmetastasispatient-derived tumor xenograftS100A10

Identifiers

PMID32976661
PMCPMC7734155
OpenAlexW3087788707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.