SynthesisKnee surgery, sports traumatology, arthroscopy : official journal of the ESSKA2021
MAKO CT-based robotic arm-assisted system is a reliable procedure for total knee arthroplasty: a systematic review.
Synthesis in Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 4 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
111 citing papers in PubMed, 4 syntheses or guidelines pooled it, 186 citations in OpenAlex.
- Cementless versus cemented fixation in robotic-assisted total knee arthroplasty: a systematic review and meta-analysis.Journal of robotic surgery · 2026Pooled it
- Intraoperative Angle Measurement of Anatomical Structures: A Systematic Review.Sensors (Basel, Switzerland) · 2024Pooled it
- Systematic review and meta-analysis of economic and healthcare resource utilization outcomes for robotic versus manual total knee arthroplasty.Journal of robotic surgery · 2023Pooled it
- Robotic-arm assisted total knee arthroplasty is associated with improved accuracy and patient reported outcomes: a systematic review and meta-analysis.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2022Pooled it
- Differences in the coronal plane alignment of the knee (CPAK) measurements using long-leg radiographs and computed tomography.Archives of orthopaedic and trauma surgery · 2026Trial
- Efficiency assessment of intelligent patient-specific instrumentation in total knee arthroplasty: a prospective randomized controlled trial.Journal of orthopaedic surgery and research · 2024Trial
- Radiographic evaluation of robot-assisted versus manual total hip arthroplasty: a multicenter randomized controlled trial.Journal of orthopaedics and traumatology : official journal of the Italian Society of Orthopaedics and Traumatology · 2024Trial
- Early Clinical and Radiographic Outcomes of Robot-Assisted Versus Conventional Manual Total Knee Arthroplasty: A Randomized Controlled Study.Orthopaedic surgery · 2022Trial
- Trial
- Early revision rate in robotic-assisted versus conventional total knee arthroplasty: a prospective cohort study 2021-2023 from the Finnish Arthroplasty Register.Acta orthopaedica · 2026Article
- Comparative Study of Post-operative Pain and Functional Outcomes in Robotic-assisted Total Knee Replacement versus Cruciate-retaining Manual Total Knee Replacement.Journal of orthopaedic case reports · 2026Article
- Asia-Pacific expert consensus on robotic-assisted hip and knee arthroplasty.Arthroplasty (London, England) · 2026Review
- Robotic-assisted total knee arthroplasty: radiological precision, clinical outcomes, and benchmarks for emerging systems.Journal of robotic surgery · 2026Review
- Comparison of early postoperative activity-related pain burden after conventional, navigation-assisted, and robotic-assisted total knee arthroplasty: a retrospective cohort study based on 24-72 h pain area under the curve.Journal of robotic surgery · 2026Article
- Article
- [Domestic ROPA surgical robot for total hip arthroplasty: An artificial bone experiments].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2026Article
- Mako robot-assisted unicompartmental knee arthroplasty mitigates the impact of surgeon handedness.Journal of robotic surgery · 2026Article
- Learning curve in image-based robotic assisted total knee arthroplasty: a MAKO-robot experience.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2026Observational
- From empirical to analytical: synergizing robotic assistance with customized implants for superior TKA outcomes.Journal of orthopaedic surgery and research · 2026Article
- Comparison of the Reliability and Gap Differences Between Using the Varus-Valgus Stress Technique and Paddles Technique in Pre-Resection Balancing Phase of Robotic-Assisted Total Knee Arthroplasty.Arthroplasty today · 2026Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to investigate the clinical and radiological results of the MAKO CT-based robotic-assisted system for total knee arthroplasty (TKA).
methodsA PRISMA systematic review was conducted using four databases (MEDLINE, EMBASE, Pubmed, GOOGLE SCHOLAR) to identify all clinical and radiological studies reporting information regarding the use and results of the CT-based robotic-assisted system to perform TKA between 2016 and 2020. The main investigated outcome criteria were postoperative pain, analgesia requirements, clinical scores, knee range of motion, implant positioning and the revision rate. The ROBINS-I tool (Risk Of Bias In Non-randomized Studies of Interventions) was used to evaluate the quality of included studies and the risk of bias.
resultsA total of 36 studies were identified, of which 26 met inclusion criteria. Of these 26 studies, 14 were comparative. The follow-up varied from 30 days to 17 months. This CT-based, saw cutting Robotic TKA is associated with a significantly lower postoperative pain score (2.6 versus 4.5) and with significantly reduced time to hospital discharge (77 h versus 105), compared with conventional TKA. The two comparative studies assessing functional outcomes at 1 year reported significantly better functional scores with CT-based robotic TKA compared with conventional TKA (WOMAC score: 6 ± 6 versus 9 ± 8 (p < 0.05); KSS function score: 80 versus 73 (p = 0.005)). Only three comparative studies assessed implant positioning, and these reported better implant positioning with CT-based robotic-assisted TKA.
conclusionThe CT-based robotic-assisted system for TKA reduced postoperative pain and improved implant positioning with equal or slightly superior improvement of the functional outcomes at one year, compared to conventional TKA. LEVEL OF EVIDENCE: Systematic review level IV.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.