Evidence map›Paper›PMID 32975604›Full record

ArticlePediatric cardiology2021

Impaired left atrial function in adults and adolescents with corrected aortic coarctation.

Fabien Labombarda, Maud Bonopéra, Pascale Maragnes, Paul Milliez, Alain Manrique, Farzin Beygui

Abstract read
PubMed Publisher
In one paragraph

Article in Pediatric cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 18 citations in OpenAlex.

  1. Observational
  2. Article
  3. Article
  4. Article
  5. Hypertension in aortic coarctation.Frontiers in cardiovascular medicine · 2025
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Relationship between left atrial myopathy and atrial fibrillation in adults with coarctation of aorta.American heart journal plus : cardiology research and practice · 2023
    Article
  11. Article
  12. Prognostic Value of the HJACC. Advances · 2022
    Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fabien LabombardaDepartment of Cardiology, CHU de Caen, Avenue cote de nacre, 14000, Caen, France. fabien.labombarda@gmail.com.
Maud BonopéraDepartment of Cardiology, CHU de Caen, Avenue cote de nacre, 14000, Caen, France.
Pascale MaragnesDepartment of Cardiology, CHU de Caen, Avenue cote de nacre, 14000, Caen, France.
Paul MilliezDepartment of Cardiology, CHU de Caen, Avenue cote de nacre, 14000, Caen, France.
Alain ManriqueMedical School, UNICAEN, CHU Caen, Université Caen Normandie, 4650, Caen, EA, France.
Farzin BeyguiDepartment of Cardiology, CHU de Caen, Avenue cote de nacre, 14000, Caen, France.
Université de Caen Normandie · FRCentre Hospitalier Universitaire de Caen Normandie · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study examined the left atrial (LA) function using two-dimensional (2D) strain analysis after aortic coarctation (CoA) repair, as well as relationships between LA function and patient characteristics, especially aortic arch anatomy. 56 patients (34 males, age: 31 ± 16 years) with CoA repair (46 post 'end-to-end anastomosis/subclavian flap') and 56 controls were studied. 2D strain imaging was performed to assess left ventricular (LV) and LA functions including peak-positive LA strain, early and late diastolic LA strains, and global longitudinal (LV-GLS) and circumferential (LV-GCS) strains. LA dysfunction (LAD) was defined as a peak-positive LA strain value lower than the mean value of the control group minus 2 SDs. Peak-positive LA strain, early and late diastolic LA strains, and LV-GLS were significantly lower in the CoA group while LV-GCS did not differ. No significant correlation was found between LA strain and either current age, age at initial repair, or blood pressure; Ea and LV-GLS were moderately correlated to peak-positive LA strain (r = 0.49, p < 0.001 and r =  - 0.55, p < 0.001, respectively). 23 CoA patients (41%) presented LAD (abnormal peak-positive LA strain < 25%). Among patients who underwent end-to-end anastomosis/subclavian flap, those with a non-romanesque aortic arch anatomy exhibited a significantly lower peak-positive LA strain. Ischemic stroke and atrial arrhythmia were more frequent in CoA patients with LAD. Our findings suggest that LAD may be prevalent late after CoA repair. Postoperative aortic arch anatomy may impact peak-positive LA strain.

Indexed as

Atrial Function, LeftAdolescentAdultAorta, ThoracicAortic CoarctationCase-Control StudiesFemaleHeart VentriclesHumansMaleMiddle AgedRetrospective StudiesVascular Surgical ProceduresVentricular Dysfunction, LeftYoung AdultCorrected aortic coarctationLeft atrial dysfunctionLeft atrial functionLeft ventricular strain

Identifiers

PMID32975604
OpenAlexW3089181659

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.