RevieweLife2020
Symbiont-mediated cytoplasmic incompatibility: what have we learned in 50 years?
Review in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 99 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
99 citing papers in PubMed, 176 citations in OpenAlex.
- Wolbachia strain wLhui induces temperature-dependent incomplete cytoplasmic incompatibility in the invasive pest Liriomyza huidobrensis with biocontrol potential.Pest management science · 2026Article
- Pervasive effects ofbioRxiv : the preprint server for biology · 2026Article
- Calibrating and documenting host-switching and evolution of incompatibility loci for two closely related Wolbachia clades.Genetics · 2026Article
- Article
- Climate predictsbioRxiv : the preprint server for biology · 2026Article
- Wolbachia-driven host miRNAs mediate arthropod reproduction in a Wolbachia density-dependent manner.Communications biology · 2026Article
- Spiroplasma Display an Intricate Continuum of Infection Heterogeneity and Persistence in Myrmica Ants.Molecular ecology · 2026Article
- Counting cytoplasmic incompatibility factor mRNA using digital droplet PCR.Microbiology spectrum · 2026Article
- Extensive mobilome dynamics in a widespread endosymbiont: long read metagenomics reveal dimeric plasmids and highly fragmented prophages in Wolbachia from Culex pipiens.Research square · 2026Article
- Calibrating and documenting host-switching and evolution of incompatibility loci for two closely relatedbioRxiv : the preprint server for biology · 2026Article
- Symbiont-mediated feminization imposes unavoidable host fitness costs.Frontiers in microbiology · 2026Article
- Article
- A co-speciation dilemma and a lifestyle transition with genomic consequences in Wolbachia of Neotropical Drosophila.BMC genomics · 2025Article
- Histone acetylation modulation by a small molecule inhibitor recapitulates symbiont-induced cytoplasmic incompatibility.Cell reports · 2025Article
- Evolutionary Diversification and Functions of the Candidate Male Killing Gene wmk.Genome biology and evolution · 2025Article
- Diversity and spread of cytoplasmic incompatibility genes among maternally inherited symbionts.PLoS genetics · 2025Article
- Stochastic Fluctuations of the Facultative EndosymbiontEcology and evolution · 2025Article
- Both maternal and paternal genotypes modulate Wolbachia-induced cytoplasmic incompatibility in graham bean beetles.Heredity · 2025Article
- Hybrid incompatibility emerges at the one-cell stage in interspecies Caenorhabditis embryos.Current biology : CB · 2025Article
- Heritable symbiont producing nonribosomal peptide confers extreme heat sensitivity and antifungal protection on its host.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
39 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Cytoplasmic incompatibility (CI) is the most common symbiont-induced reproductive manipulation. Specifically, symbiont-induced sperm modifications cause catastrophic mitotic defects in the fertilized embryo and ensuing lethality in crosses between symbiotic males and either aposymbiotic females or females harboring a different symbiont strain. However, if the female carries the same symbiont strain, then embryos develop properly, thereby imparting a relative fitness benefit to symbiont-transmitting mothers. Thus, CI drives maternally-transmitted bacteria to high frequencies in arthropods worldwide. In the past two decades, CI experienced a boom in interest due to its (i) deployment in worldwide efforts to curb mosquito-borne diseases, (ii) causation by bacteriophage genes,
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.