ArticlePreventing chronic disease2020
State and Regional Variation in Prescription- and Payment-Related Promoters of Adherence to Blood Pressure Medication.
Article in Preventing chronic disease, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 15 citations in OpenAlex.
- Medicaid coverage for fixed-dose combination antihypertensive medications - fifty states and Washington, D.C., 2022.Journal of human hypertension · 2026Article
- Factors affecting cost-related medication non-adherence among US population with cardiovascular risk factors.Primary health care research & development · 2026Article
- Effect of Systolic Blood Pressure Measurement Error on the Cost-Effectiveness of Intensive Blood Pressure Targets.Annals of internal medicine · 2025Article
- Geographic Variation in Persistence of Oral Anticoagulant Treatment Among Patients with Non-Valvular Atrial Fibrillation in the United States.Journal of clinical medicine · 2025Article
- Implications of the South African National Drug Policy on prescribing patterns: a case study of the Limpopo province.Journal of pharmaceutical policy and practice · 2023Article
- Prescription Smoking-Cessation Medication Fills and Spending, 2009-2019.American journal of preventive medicine · 2022Article
- County-Level Trends in Hypertension-Related Cardiovascular Disease Mortality-United States, 2000 to 2019.Journal of the American Heart Association · 2022Article
- Cost-Effectiveness of Recommendations From the Surgeon General's Call-to-Action to Control Hypertension.American journal of hypertension · 2022Review
- Patient access to chronic medications during the Covid-19 pandemic: Evidence from a comprehensive dataset of US insurance claims.PloS one · 2021Article
- Association of Perceived Stress and Discrimination on Medication Adherence among Diverse Patients with Uncontrolled Hypertension.Ethnicity & disease · 2021Article
- Pharmacy Contributions to Improved Population Health: Expanding the Public Health Roundtable.Preventing chronic disease · 2020Article
Corrections and comments
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Authors and funding
5 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionMedication adherence can improve hypertension management. How blood pressure medications are prescribed and purchased can promote or impede adherence.
methodsWe used comprehensive dispensing data on prescription blood pressure medication from Symphony Health's 2017 Integrated Dataverse to assess how prescription- and payment-related factors that promote medication adherence (ie, fixed-dose combinations, generic formulations, mail order, low-cost or no-copay medications) vary across US states and census regions and across the market segments (grouped by patient age, prescriber type, and payer type) responsible for the greatest number of blood pressure medication fills.
resultsIn 2017, 706.5 million prescriptions for blood pressure medication were filled, accounting for $29.0 billion in total spending (17.0% incurred by patients). As a proportion of all fills, factors that promoted adherence varied by state: fixed-dose combinations (from 5.8% in Maine to 17.9% in Mississippi); generic formulations (from 95.2% in New Jersey to 98.4% in Minnesota); mail order (from 4.7% in Rhode Island to 14.5% in Delaware); and lower or no copayment (from 56.6% in Utah to 72.8% in California). Furthermore, mean days' supply per fill (from 43.1 in Arkansas to 63.8 in Maine) and patient spending per therapy year (from $38 in Hawaii to $76 in Georgia) varied. Concentration of adherence factors differed by market segment. Patients aged 18 to 64 with a primary care physician prescriber and Medicaid coverage had the lowest concentration of fixed-dose combination fills, mean days' supply per fill, and patient spending per therapy year. Patients aged 65 years or older with a primary care physician prescriber and commercial insurance had the highest concentration of fixed-dose combinations fills and mail order fills.
conclusionAddressing regional and market segment variation in factors promoting blood pressure medication adherence may increase adherence and improve hypertension management.
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