Evidence map›Paper›PMID 32975469›Full record

ReviewNanomedicine (London, England)2020

Current trends in pyrrole and porphyrin-derived nanoscale materials for biomedical applications.

Parinaz Fathi, Dipanjan Pan

Abstract readReview
In one paragraph

Review in Nanomedicine (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Parinaz FathiDepartments of Bioengineering, Materials Science & Engineering & Beckman Institute, University of Illinois, Urbana, IL 61801, USA.ORCID 0000-0003-1639-5687
Dipanjan PanDepartments of Bioengineering, Materials Science & Engineering & Beckman Institute, University of Illinois, Urbana, IL 61801, USA.ORCID 0000-0003-0175-4704

Funding

Tissue microenvironment (TIMe) training programT32EB019944 · NIBIB · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI BHARGAVA, ROHIT, GASKINS, REX · 2016 to 2025
$1.9M
A Sensing Platform for Rapid at Home-Test of COVID-19R03EB028026 · NIBIB · UNIVERSITY OF MARYLAND BALTIMORE COUNTY · PI PAN, DIPANJAN · 2019 to 2020
$300k
NIBIB NIH HHS R03 EB028026NIBIB NIH HHS T32 EB019944
6 · The paper itself

Abstract

This article is written to provide an up-to-date review of pyrrole-based biomedical materials. Porphyrins and other tetrapyrrolic molecules possess unique magnetic, optical and other photophysical properties that make them useful for bioimaging and therapy. This review touches briefly on some of the synthetic strategies to obtain porphyrin- and tetrapyrrole-based nanoparticles, as well as the variety of applications in which crosslinked, self-assembled, porphyrin-coated and other nanoparticles are utilized. We explore examples of these nanoparticles' applications in photothermal therapy, drug delivery, photodynamic therapy, stimuli response, fluorescence imaging, photoacoustic imaging, magnetic resonance imaging, computed tomography and positron emission tomography. We anticipate that this review will provide a comprehensive summary of pyrrole-derived nanoparticles and provide a guideline for their further development.

Indexed as

NanoparticlesOptical ImagingPhotochemotherapyPorphyrinsPyrrolesPorphyrinsPyrrolesbioimagingcarbon dotsdrug deliverynanoparticlesporphyrinporphysomestetrapyrrolestheranostic

Identifiers

PMID32975469
PMCPMC7610151

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.