Evidence map›Paper›PMID 32975211›Full record

ArticleMolecules and cells2020

Peroxiredoxin 3 Has Important Roles on Arsenic Trioxide Induced Apoptosis in Human Acute Promyelocytic Leukemia Cell Line via Hyperoxidation of Mitochondrial Specific Reactive Oxygen Species.

Yeung-Chul Mun, Jee Young Ahn, Eun Sun Yoo, Kyoung Eun Lee, Eun Mi Nam, Jungwon Huh, Hyun Ae Woo, Sue Goo Rhee, Chu Myong Seong

Open access · greenAbstract read
In one paragraph

Article in Molecules and cells, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Review
  6. Hyperoxidation of Peroxiredoxins and Effects on Physiology ofAntioxidants (Basel, Switzerland) · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yeung-Chul MunDepartment of Hematology and Oncology, Ewha Womans University College of Medicine, Seoul 07985, Korea.ORCID https://orcid.org/0000-0002-1882-3983
Jee Young AhnDepartment of Hematology and Oncology, Ewha Womans University College of Medicine, Seoul 07985, Korea.ORCID https://orcid.org/0000-0002-9813-0481
Eun Sun YooDepartment of Pediatrics, Ewha Womans University College of Medicine, Seoul 07985, Korea.ORCID https://orcid.org/0000-0001-6419-2337
Kyoung Eun LeeDepartment of Hematology and Oncology, Ewha Womans University College of Medicine, Seoul 07985, Korea.ORCID https://orcid.org/0000-0003-1596-8666
Eun Mi NamDepartment of Hematology and Oncology, Ewha Womans University College of Medicine, Seoul 07985, Korea.ORCID https://orcid.org/0000-0003-0108-5352
Jungwon HuhDepartment of Laboratory Medicine, Ewha Womans University College of Medicine, Seoul 07985, Korea.ORCID https://orcid.org/0000-0001-8758-9847
Hyun Ae WooGraduate School of Pharmaceutical Sciences, Ewha Womans University, Seoul 03760, Korea.ORCID https://orcid.org/0000-0002-3483-1203
Sue Goo RheeYonsei Biomedical Research Institute, Yonsei University College of Medicine, Seoul 03722, Korea.ORCID https://orcid.org/0000-0002-4740-4956
Chu Myong SeongDepartment of Hematology and Oncology, Ewha Womans University College of Medicine, Seoul 07985, Korea.ORCID https://orcid.org/0000-0001-9985-9218
Ewha Womans University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

NB4 cell, the human acute promyelocytic leukemia (APL) cell line, was treated with various concentrations of arsenic trioxide (ATO) to induce apoptosis, measured by staining with 7-amino-actinomycin D (7-AAD) by flow cytometry. 2', 7'-dichlorodihydro-fluorescein-diacetate (DCF-DA) and MitoSOX

Indexed as

Antineoplastic AgentsApoptosisArsenic TrioxideCell Line, TumorHumansLeukemia, Promyelocytic, AcuteMitochondriaPeroxiredoxin IIIReactive Oxygen SpeciesTransfectionAntineoplastic AgentsArsenic TrioxidePeroxiredoxin IIIReactive Oxygen Speciesacute promyelocytic leukemiaarsenic trioxideperoxiredoxin 3

Identifiers

PMID32975211
PMCPMC7528683
OpenAlexW3089312342

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.