Evidence map›Paper›PMID 32975131›Full record

Trial reportDiabetes & vascular disease research

Timed physical exercise does not influence circadian rhythms and glucose tolerance in rotating night shift workers: The EuRhythDia study.

Juliane Hannemann, Anika Laing, Karin Glismann, Debra J Skene, Benita Middleton, Bart Staels, Nikolaus Marx, Peter J Grant, Massimo Federici, Josef Niebauer and 1 more

Open access · diamondAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Diabetes & vascular disease research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 3 pooled it
0.8field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 3 syntheses or guidelines pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Shift Work and Early Arterial Stiffness: A Systematic Review.International journal of environmental research and public health · 2022
    Pooled it
  3. Pooled it
  4. Efficacy and Adherence to a Supervised Aerobic Exercise Training Intervention in Night-Shift Hospital Nurses: A Randomized Controlled Trial.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Trial
  5. Review
  6. Review
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 5 countries.

Juliane HannemannInstitute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-3499-4827
Anika LaingInstitute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Karin GlismannInstitute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.
Debra J SkeneChronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Benita MiddletonChronobiology, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK.
Bart StaelsUniv. Lille, Inserm, CHU Lille, Institut Pasteur de Lille, U1011-EGID, Lille, France.
Nikolaus MarxDepartment of Cardiology, University Medical Center Aachen, Aachen, Germany.
Peter J GrantLeeds Institute of Cardiovascular and Metabolic Medicine, University of Leeds, Leeds, UK.
Massimo FedericiCenter for Atherosclerosis, School of Medicine, University of Rome 'Tor Vergata', Rome, Italy.
Josef NiebauerUniversity Institute for Preventive and Rehabilitative Sports Medicine, Paracelsus Medical University, Salzburg, Austria.
Rainer BögerInstitute of Clinical Pharmacology and Toxicology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany.ORCID 0000-0003-3770-5357
Universität Hamburg · DEUniversity of Surrey · GBInserm · FRParacelsus Medical University · ATUniversity of Leeds · GBUniversity of Rome Tor Vergata · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesNight shift workers are at cardiometabolic risk due to circadian misalignment. We investigated whether infrequent exercise before each night shift that intentionally would not improve physical performance improves glucose tolerance and 24-h blood pressure profiles and synchronizes circadian rhythms of melatonin and cortisol in rotating night shift workers.

methodsA total of 24 rotating night shift workers (mean age, 35.7 ± 11.8 years) were randomized to exercise or no intervention. Workers in the exercise group performed 15.2 ± 4.5 exercise sessions within 2 h before each night shift. Before and after 12 weeks of exercise intervention and 12 weeks after the intervention, spiroergometry, oral glucose tolerance testing and 24-h blood pressure profiles were performed. Plasma melatonin and cortisol levels were measured in 3-hourly intervals during one 24-h period on each study day.

resultsExercise did not significantly change serum glucose nor insulin levels during oral glucose tolerance testing. Timed physical exercise had no effect on physical performance, nor did it change the circadian rhythms of melatonin and cortisol or influence 24-h blood pressure profiles.

conclusionPhysical exercise before each night shift at a low intensity level that does not improve physical performance does not affect circadian timing, glucose tolerance or 24-h blood pressure profiles in rotating night shift workers.

Indexed as

Blood PressureCircadian RhythmExerciseShift Work ScheduleAdultBiomarkersBlood GlucoseBlood Pressure Monitoring, AmbulatoryFemaleGlucose Tolerance TestHumansHydrocortisoneInsulinMaleMelatoninMiddle AgedBiomarkersBlood GlucoseHydrocortisoneInsulinMelatonindiabetes mellitusglucose toleranceinsulinNight shift workersprospective studyvascular stiffness

Identifiers

PMID32975131
PMCPMC7919228
OpenAlexW3088490407

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.