Evidence map›Paper›PMID 32975062›Full record

ArticleYonsei medical journal2020

Analysis of Adverse Drug Reactions with Carbamazepine and Oxcarbazepine at a Tertiary Care Hospital.

Jung Eun Lee, Kang Ryul Min, Soo Hyun Kim, Alec Hyungtack Kim, Seong Taek Kim

Open access · goldAbstract read
In one paragraph

Article in Yonsei medical journal, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
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  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Jung Eun LeeDepartment of Orofacial Pain and Oral Medicine, Yonsei University College of Dentistry, Seoul, Korea.ORCID https://orcid.org/0000-0001-6439-8087
Kang Ryul MinDepartment of Biology, Lake Forest College, Lake Forest, IL, USA.ORCID https://orcid.org/0000-0003-4621-7048
Soo Hyun KimDepartment of Pharmacy, Yonsei University Healthcare System, Seoul, Korea.ORCID https://orcid.org/0000-0001-9852-8484
Alec Hyungtack KimTMJ & Orofacial Pain Clinic, University of California, Los Angeles, CA, USA.ORCID https://orcid.org/0000-0003-3999-4818
Seong Taek KimDepartment of Orofacial Pain and Oral Medicine, Yonsei University College of Dentistry, Seoul, Korea. k8756050@yuhs.ac.ORCID https://orcid.org/0000-0001-9506-5103
Yonsei University · KRLake Forest College · USUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo describe adverse drug reactions (ADRs) to carbamazepine (CBZ) and oxcarbazepine (OXC), including severe cutaneous ADRs, at a tertiary care hospital over a 10-year period. MATERIALS AND

methodsThe frequency and clinical features of ADRs caused by CBZ and OXC were analyzed using the pharmacovigilance database and spontaneous ADR reporting data of Yonsei University Severance Hospital & Dental Hospital (Seoul, Korea) from January 1, 2010 to January 31, 2020.

resultsAmong 10419 cases prescribed CBZ and OXC, 204 ADR cases were reported. The incidences of ADRs were 1.8% and 2.2% for CBZ and OXC respectively, with no significant difference (

conclusionDue to lower incidence of severe ADRs with OXC than CBZ, we suggest OXC as a first-line prescription.

Indexed as

AdolescentAdultAgedAnticonvulsantsBipolar DisorderCarbamazepineDrug-Related Side Effects and Adverse ReactionsEpilepsyFemaleHumansIncidenceMaleMiddle AgedNeuralgiaOxcarbazepinePharmacovigilanceAnticonvulsantsCarbamazepineOxcarbazepineanticonvulsantsCarbamazepinedrug related adverse reactionsoxcarbazepine

Identifiers

PMID32975062
PMCPMC7515781
OpenAlexW3088942438

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.