Evidence map›Paper›PMID 32975041›Full record

ArticleChemMedChem2021

Evaluation of a Platinum-Acridine Anticancer Agent and Its Liposomal Formulation in an in vivo Model of Lung Adenocarcinoma.

Song Ding, Christopher L Hackett, Fang Liu, Ryan G Hackett, Ulrich Bierbach

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ChemMedChem, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Song DingDepartment of Chemistry, Wake Forest University, 1834 Wake Forest Road, Winston-Salem, NC, 27109, USA.
Christopher L HackettDepartment of Chemistry, Wake Forest University, 1834 Wake Forest Road, Winston-Salem, NC, 27109, USA.
Fang LiuDepartment of Chemistry, Wake Forest University, 1834 Wake Forest Road, Winston-Salem, NC, 27109, USA.
Ryan G HackettDepartment of Chemistry, Wake Forest University, 1834 Wake Forest Road, Winston-Salem, NC, 27109, USA.
Ulrich BierbachDepartment of Chemistry, Wake Forest University, 1834 Wake Forest Road, Winston-Salem, NC, 27109, USA.ORCID 0000-0001-5658-7662
Wake Forest University · US

Funding

Novel DNA-metalating Hybrid Anticancer AgentsR01CA101880 · NCI · WAKE FOREST UNIVERSITY · PI BIERBACH, ULRICH · 2003 to 2012
$1.8M
NCI NIH HHS R01 CA101880
6 · The paper itself

Abstract

Liposomal formulations have been developed for a highly cytotoxic platinum-acridine agent, [PtCl(pn)(C

Indexed as

Models, BiologicalA549 CellsAcridinesAdenocarcinoma of LungAnimalsAntineoplastic AgentsCell ProliferationDrug CompoundingDrug Screening Assays, AntitumorFemaleHumansLiposomesLung NeoplasmsMiceMice, NudeMolecular StructureAcridinesAntineoplastic AgentsLiposomesOrganoplatinum CompoundsPlatinumantitumor agentsdrug deliverylung cancerplatinum-acridine hybrid agentsxenografts

Identifiers

PMID32975041
PMCPMC8057267
OpenAlexW3087848432

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.