Evidence map›Paper›PMID 32974687›Full record

ArticleEuropean radiology2021

MR 4D flow-based mean pulmonary arterial pressure tracking in pulmonary hypertension.

Ursula Reiter, Gabor Kovacs, Clemens Reiter, Corina Kräuter, Volha Nizhnikava, Michael Fuchsjäger, Horst Olschewski, Gert Reiter

2 registry-linked trialsOpen access · hybridAbstract read
In one paragraph

Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00575692 completednot on this map

Magnetic Resonance Imaging in the Diagnosis of Pulmonary Hypertension

TypeobservationalSponsorMedical University of GrazRan2006 to 2013Enrolled240ConditionsPulmonary Hypertension, Ventricular Function, MR Phase Contrast Velocity Imaging, Late Enhancement Patterns
NCT01725763 naenrolling by invitationnot on this map

Non-contrast Enhanced Cardiac Magnetic Resonance Imaging in the Diagnosis and Classification of Pulmonary Hypertension

TypeinterventionalSponsorMedical University of GrazRan2012 to 2030Enrolled150ConditionsPulmonary Hypertension, Elevated Mean Pulmonary Arterial Pressure, Normal Mean Pulmonary Arterial PressureArmsCardiac MRI
3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 40 citations in OpenAlex.

  1. Pooled it
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  5. Review
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  12. A Non-Invasive Approach to Pulmonary Hypertension.Journal of clinical medicine · 2025
    Review
  13. Review
  14. Article
  15. Review
  16. Article
  17. Article
  18. Characterization of pulmonary arterial stiffness using cardiac MRI.The international journal of cardiovascular imaging · 2024
    Review
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ursula ReiterDivision of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria. ursula.reiter@medunigraz.at.ORCID http://orcid.org/0000-0002-4374-2528
Gabor KovacsDivision of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Clemens ReiterDivision of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
Corina KräuterDivision of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
Volha NizhnikavaDivision of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
Michael FuchsjägerDivision of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
Horst OlschewskiDivision of Pulmonology, Department of Internal Medicine, Medical University of Graz, Graz, Austria.
Gert ReiterDivision of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
Medical University of Graz · AT

Funding

European School of Radiology ESOR One-year fellowship 2019Oesterreichische Nationalbank 17934
6 · The paper itself

Abstract

objectivesLongitudinal hemodynamic follow-up is important in the management of pulmonary hypertension (PH). This study aimed to evaluate the potential of MR 4-dimensional (4D) flow imaging to predict changes in the mean pulmonary arterial pressure (mPAP) during serial investigations.

methodsForty-four adult patients with PH or at risk of developing PH repeatedly underwent routine right heart catheterization (RHC) and near-term MR 4D flow imaging of the main pulmonary artery. The duration of vortical blood flow along the main pulmonary artery was evaluated from MR 4D velocity fields using prototype software and converted to an MR 4D flow imaging-based mPAP estimate (mPAP

resultsAreas under the curve for the prediction of mPAP increases and decreases were 0.92 and 0.93, respectively. With the natural cutoff ΔmPAP

conclusionsMR 4D flow imaging allows accurate non-invasive prediction and quantification of mPAP changes in adult patients with PH or at risk of developing PH.

trial registrationClinicalTrials.gov identifier: NCT00575692 and NCT01725763 KEY POINTS: • MR 4D flow imaging allows accurate non-invasive prediction of mean pulmonary arterial pressure increases and decreases in adult patients with or at risk of developing pulmonary hypertension. • In adult patients with mean pulmonary arterial pressure > 16 mmHg, MR 4D flow imaging allows estimation of longitudinal mean pulmonary arterial pressure changes without bias with a standard deviation of 5.1 mmHg.

Indexed as

Hypertension, PulmonaryAdultArterial PressureCardiac CatheterizationHemodynamicsHumansPulmonary ArteryFollow-up studiesHemodynamicsMagnetic resonance imagingPulmonary hypertension

Identifiers

PMID32974687
PMCPMC7979582
OpenAlexW3088178937

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.