Evidence map›Paper›PMID 32974645›Full record

ArticleInternational journal of epidemiology2021

Maternal life and work stressors during pregnancy and asthma in offspring.

Kathrine Pape, Xiaoqin Liu, Camilla Sandal Sejbæk, Niklas Worm Andersson, Ann Dyreborg Larsen, Hans Bay, Henrik Albert Kolstad, Jens Peter Ellekilde Bonde, Jørn Olsen, Cecilie Svanes and 4 more

Open access · bronzeAbstract read
In one paragraph

Article in International journal of epidemiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Maternal stressful life events during pregnancy and childhood asthma and wheeze.Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 2 countries.

Kathrine PapeDepartment of Public Health, Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.
Xiaoqin LiuNCRR-National Centre for Register-based Research, Department of Economics and Business Economics, Aarhus University, Denmark.
Camilla Sandal SejbækNational Research Centre for the Working Environment, Copenhagen, Denmark.
Niklas Worm AnderssonDepartment of Public Health, Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.
Ann Dyreborg LarsenNational Research Centre for the Working Environment, Copenhagen, Denmark.
Hans BayNational Research Centre for the Working Environment, Copenhagen, Denmark.
Henrik Albert KolstadDepartment of Occupational Medicine, Danish Ramazzini Centre, Aarhus University Hospital, Denmark.
Jens Peter Ellekilde BondeDepartment of Occupational and Environmental Medicine, Bispebjerg and Frederiksberg Hospitals, Copenhagen, Denmark.
Jørn OlsenDepartment of Clinical Medicine, Department of Clinical Epidemiology, Aarhus University, Denmark.
Cecilie SvanesUniversity of Bergen, Department of Global Public Health and Primary Care, Bergen, Norway.
Kirsten Skamstrup HansenDepartment of Paediatrics, Herlev and Gentofte Hospital, Hellerup, Denmark.
Reiner RuguliesNational Research Centre for the Working Environment, Copenhagen, Denmark.
Karin Sørig HougaardNational Research Centre for the Working Environment, Copenhagen, Denmark.
Vivi SchlünssenDepartment of Public Health, Environment, Occupation and Health, Danish Ramazzini Centre, Aarhus University, Aarhus, Denmark.
Aarhus University · DKNational Research Centre for the Working Environment · DKUniversity of Copenhagen · DKGentofte Hospital · DKHaukeland University Hospital · NOStatens Serum Institut · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundMaternal stressors during pregnancy are potential risk factors for asthma in offspring. However, previous studies have been limited by the use of self-reported data focusing on stressors either in private life or at work. This study examined the association between maternal stressors both in private life and at work during pregnancy and asthma in offspring.

methodsIn the Danish National Birth Cohort, 75 156 live-born singletons born during 1996-2002 were identified. Maternal information on job title were available around weeks 12-16 of gestation. Data on maternal bereavement, life-threatening illness, suicide attempt and alcohol or drug abuse of a close relative and offspring childhood asthma (3-10 years of age) were obtained from Danish nationwide registers. Maternal psychosocial work stressors (job control, psychological job demands, emotional job demands, work-related violence and threats of work-related violence) were estimated by the use of job-exposure matrices. The association between maternal stress and childhood asthma was analysed in Cox models adjusted for maternal age, comorbidity and parity.

resultsNeither private-life nor work stressors were related to onset of asthma in offspring. Separate analyses by parental atopy or onset of asthma in offspring supported the main findings.

conclusionsThis study does not support an elevated risk of childhood asthma related to exposure to stress during pregnancy.

Indexed as

AsthmaPrenatal Exposure Delayed EffectsFemaleHumansMothersPregnancyRisk FactorsStress, Psychologicalbereavementchildhood asthmajob-exposure matrixNegative life eventsoccupational exposurestress

Identifiers

PMID32974645
PMCPMC7825935
OpenAlexW3087994322

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.