Evidence map›Paper›PMID 32974413›Full record

ArticleEye and vision (London, England)2020

Morphological features of anterior segment: factors influencing intraocular pressure after cataract surgery in nanophthalmos.

Qiang Lu, Wenwen He, Yi Lu, Xiangjia Zhu

Registry-linked trialAbstract read
In one paragraph

Article in Eye and vision (London, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02182921 (Evaluation of Surgical Outcomes of Cataract Surgery), which is not on this map. Cited by 4 papers, 1 of them a synthesis that pooled it.

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4citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02182921 recruitingnot on this map

Evaluation of Surgical Outcomes of Cataract Surgery

TypeobservationalSponsorEvidence Based Cataract Study GroupRan2013 to 2030Enrolled20,000ConditionsCataract, High Myopia
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Qiang LuDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031 People's Republic of China.
Wenwen HeDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031 People's Republic of China.
Yi LuDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031 People's Republic of China.
Xiangjia ZhuDepartment of Ophthalmology, Eye and Ear, Nose, and Throat Hospital, Fudan University, 83 Fenyang Road, Shanghai, 200031 People's Republic of China.ORCID 0000-0001-5588-1667

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the anterior segment in nanophthalmic eyes and their association with intraocular pressure after cataract surgery.

methodsThirty-two nanophthalmic eyes (axial length [AL] < 18.5 mm) in 18 patients and 35 normal eyes (21 ≤ AL ≤ 24.5 mm) in 35 controls who had undergone uneventful cataract surgery were included. Swept-source optical coherence tomography was used to compare the anterior segment structures between the two groups. The associations between the anterior segment characteristics of nanophthalmic eyes and postoperative intraocular pressure (IOP) were also investigated.

resultsThe IOP-lowering effect of cataract surgery was remarkably insufficient in nanophthalmic eyes. Peripheral anterior synechiae (PAS) were observed in 56% (18/32) of nanophthalmic eyes, and a characteristic boomerang-shaped iris was observed in 28% (9/32). The anterior surface of the iris seemed "smoother" in nanophthalmic eyes than in normal eyes. Schlemm's canal (SC) diameter, SC area, trabecular meshwork (TM) thickness, TM width, and TM area were generally smaller in the nanophthalmic eyes. Younger age, higher preoperative IOP, broader PAS, and smaller SC area were main contributors to higher postoperative IOP. AL and SC diameter may also be of great importance in IOP prediction in patients without glaucoma surgery and PAS.

conclusionsThe morphological features of the anterior segment in nanophthalmic eyes are significantly different from those of normal eyes. Influencing factors such as age, AL, preoperative IOP, extent of PAS, SC and TM size could all be prognostic for IOP after cataract surgery in nanophthalmic eyes.

trial registrationClinicalTrails.gov, Trial registration number: NCT02182921, Registered 8 July 2014.

Indexed as

Anterior segmentBoomerang-shaped irisCataract surgeryIntraocular pressureIris cryptNanophthalmosPeripheral anterior synechiaeSchlemm’s canalTrabecular meshwork

Identifiers

PMID32974413
PMCPMC7495875

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