Evidence map›Paper›PMID 32974271›Full record

ArticleFrontiers in chemistry2020

Evaluation of Pt,Pd-Doped, NiO-Decorated, Single-Wall Carbon Nanotube-Ionic Liquid Carbon Paste Chemically Modified Electrode: An Ultrasensitive Anticancer Drug Sensor for the Determination of Daunorubicin in the Presence of Tamoxifen.

Marzieh Alizadeh, Parviz Aberoomand Azar, Sayed Ahmad Mozaffari, Hassan Karimi-Maleh, Ali-Mohammad Tamaddon

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Frontiers in chemistry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Marzieh AlizadehDepartment of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Parviz Aberoomand AzarDepartment of Chemistry, Science and Research Branch, Islamic Azad University, Tehran, Iran.
Sayed Ahmad MozaffariThin Layer and Nanotechnology Laboratory, Department of Chemical Technologies, Iranian Research Organization for Science and Technology (IROST), Tehran, Iran.
Hassan Karimi-MalehLaboratory of Nanotechnology, Department of Chemical Engineering, Quchan University of Technology, Quchan, Iran.
Ali-Mohammad TamaddonCenter for Nanotechnology in Drug Delivery, School of Pharmacy, Shiraz University of Medical Sciences, Shiraz, Iran.
Islamic Azad University, Science and Research Branch · IRIranian Research Organization for Science and Technology · IRQuchan University of Advanced Technology · IRShiraz University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Measuring the concentration of anticancer drugs in pharmacological and biological samples is a very useful solution to investigate the effectiveness of these drugs in the chemotherapy process. A Pt,Pd-doped, NiO-decorated SWCNTs (Pt,Pd-NiO/SWCNTs) nanocomposite was synthesized using a one-pot procedure and combining chemical precipitation and ultrasonic sonochemical methods and subsequently characterized by TEM and EDS analysis methods. The analyses results showed the high purity and good distribution of elements and the ~10-nm diameter of the Pt,Pd-NiO nanoparticle decorated on the surface of the SWCNTs with a diameter of about 20-30 nm. Using a combination of Pt,Pd-NiO/SWCNTs and 1-butyl-2,3-dimethylimidazolium tetrafluoroborate (1B23DTFB) in a carbon paste (CP) matrix, Pt,Pd-NiO/SWCNTs/1B23DTFB/CP was fabricated as a highly sensitive analytical tool for the electrochemical determination of daunorubicin in the concentration range of 0.008-350 μM with a detection limit of 3.0 nM. Compared to unmodified CP electrodes, the electro-oxidation process of daunorubicin has undergone significant improvements in current (about 9.8 times increasing in current) and potential (about 110 mV) decreasing in potential). It is noteworthy that the designed sensor can well measure daunorubicin in the presence of tamoxifen (two breast anticancer drugs with a ΔE = 315 mV. According to the real sample analysis data, the Pt,Pd-NiO/SWCNTs/1B23DTFB/CP has proved to be a promising methodology for the analysis and measuring of daunorubicin and tamoxifen in real (e.g., pharmaceutical) samples.

Indexed as

1-butyl-2,3-dimethylimidazolium tetrafluoroboratecancer sensordaunorubicinPt,Pd-doped NiO nanoparticletamoxifen

Identifiers

PMID32974271
PMCPMC7466574
OpenAlexW3057165213

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.