Evidence map›Paper›PMID 32974171›Full record

ReviewFrontiers in oncology2020

Key Players in the Mutant p53 Team: Small Molecules, Gene Editing, Immunotherapy.

Vitaly Chasov, Regina Mirgayazova, Ekaterina Zmievskaya, Raniya Khadiullina, Aygul Valiullina, Joseph Stephenson Clarke, Albert Rizvanov, Matthias G J Baud, Emil Bulatov

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  7. Manufacturing DNA inMolecular therapy. Methods & clinical development · 2024
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  9. Journal for immunotherapy of cancer · 2023
    Article
  10. Omics-Based Investigations of Breast Cancer.Molecules (Basel, Switzerland) · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Vitaly ChasovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Regina MirgayazovaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Ekaterina ZmievskayaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Raniya KhadiullinaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Aygul ValiullinaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Joseph Stephenson ClarkeSchool of Chemistry, University of Southampton, Southampton, United Kingdom.
Albert RizvanovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Matthias G J BaudSchool of Chemistry, University of Southampton, Southampton, United Kingdom.
Emil BulatovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Kazan Federal University · RUUniversity of Southampton · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transcription factor p53 is a key tumor suppressor that is inactivated in almost all cancers due to either point mutations in the

Indexed as

adenoviral gene therapyCRISPR/Cas gene editingimmunotherapymutationp53small molecules

Identifiers

PMID32974171
PMCPMC7461930
OpenAlexW3049027001

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.