Evidence map›Paper›PMID 32974083›Full record

ArticleTranslational vision science & technology2020

Longitudinal Changes of Macular Curvature in Patients with Retinitis Pigmentosa.

Monika Meinert, Shinji Ueno, Shiori Komori, Yoshito Koyanagi, Akira Sayo, Sten Andreasson, Taro Kominami, Yasuki Ito, Hiroko Terasaki

Abstract read
In one paragraph

Article in Translational vision science & technology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Monika MeinertDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Shinji UenoDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Shiori KomoriDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Yoshito KoyanagiDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Akira SayoDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Sten AndreassonDepartment of Ophthalmology, University of Lund, Lund, Sweden.
Taro KominamiDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Yasuki ItoDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.
Hiroko TerasakiDepartment of Ophthalmology, Nagoya University Graduate School of Medicine, Showa-ku, Nagoya, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To investigate the longitudinal changes of the macular curvature in eyes with retinitis pigmentosa (RP) and to determine the factors associated with the changes. Methods: We reviewed the medical charts of 107 RP patients, for whom the axial length of their right eyes ranged from 21.5 to 26.0 mm and who had had been followed by spectral-domain optical coherence tomography (OCT). The OCT images at the initial and the most recent examinations were compared. The mean curvature of Bruch's membrane within 6 mm of the central macula obtained from the OCT images was evaluated as the mean macular curvature index (MMCI). Changes in the MMCI and their relationships with other clinical factors, including the ellipsoid zone (EZ) width, were assessed. Results: The MMCI decreased significantly in the vertical OCT images, from -15.47 × 10 Conclusions: The macular curvature in RP eyes becomes more concave in eyes with preserved EZ width. Translational Relevance: Longitudinal changes of the macular curvature in RP should be considered in future therapies, such as the implantation of the retinal prosthesis.

Indexed as

Macula LuteaMacular EdemaRetinitis PigmentosaBruch MembraneHumansTomography, Optical Coherenceellipsoid zonemacular curvatureretinal photoreceptor layerretinitis pigmentosaspectral domain optical coherence

Identifiers

PMID32974083
PMCPMC7488647

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.