ArticleTherapeutic advances in psychopharmacology2020
Rates and correlates of pharmacotherapy-related problems among psychiatric inpatients: a representative Danish study.
Article in Therapeutic advances in psychopharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.
- Prevalence and solving strategies of drug-related problems in adult psychiatric inpatients - a systematic review.Frontiers in psychiatry · 2024Pooled it
- Impact of multi-professional medication reviews (MPMRs) on medication prescriptions in psychiatry.PloS one · 2026Observational
- Antihypertensive drug-related problems in Vietnamese ambulatory care.Scientific reports · 2025Article
- Assessment of Potential Drug-Drug Interactions of Psycholeptics and Antidepressants in Outpatient Settings.Pharmacy (Basel, Switzerland) · 2024Article
- Surveying Child and Adolescent Inpatient Psychiatric Units: Demographics, Policies, and Practice.Evidence-based practice in child and adolescent mental health · 2024Article
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Authors and funding
4 authors at 2 institutions in 1 country.
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Abstract
backgroundDrug related problems (DRPs) occur frequently among psychiatric patients due to common prescribing errors and complex treatment schedules. Clinical pharmacists (CPs) are thought to play an important role in preventing DRPs and, consequently, to increasing the quality of inpatient care. There is, however, limited information available on DRPs within the psychiatric field in Denmark. The aim of this study was to identify rates and correlates of pharmacotherapy-related problems among psychiatric inpatients in a Danish psychiatric hospital.
methodsA retrospective descriptive study was conducted by two CPs and data were obtained from the medical records available in two psychiatric wards. Chart-reviews were conducted for the period of June 2015 to February 2017. The analyses focussed on the prevalence of DRP categories, implementation and acceptance rates, and drugs associated with the DRPs. Extracted data were discussed with the wards' physicians and registered in a DRP-database.
resultsIn total, 607 medical records were reviewed and, on average, 2.5 DRPs per medication review were found. There was a positive correlation between the number prescribed drugs and the average number of DRPs. The most frequent categories of DRPs were 'drug dosage', 'inappropriate drug' and 'interactions'. The drugs represented most frequently in DRPs were olanzapine, quetiapine and pantoprazole. The overall acceptance rate was 49% with 33% of those implemented clinically.
conclusionDRPs were commonly observed among psychiatric patients, particularly in those with multiple prescriptions, in relation to drugs dosage, inappropriate prescriptions and drug interactions. Particular attention must be paid to olanzapine, quetiapine and pantoprazole. Strategies to minimise DRPs among psychiatric patients are warranted and CPs can play an important role.
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