Evidence map›Paper›PMID 32973811›Full record

ArticleFrontiers in immunology2020

Targeted Co-delivery of Tumor Antigen and α-Galactosylceramide to CD141

Jing Huang, Jing Zhou, Reem Ghinnagow, Toshiyuki Seki, Sho Iketani, Daphnée Soulard, Patrick Paczkowski, Yukiko Tsuji, Sean MacKay, Luis Javier Cruz and 2 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 25 citations in OpenAlex.

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  14. A humanized mouse model forFrontiers in immunology · 2022
    Article
  15. Article
  16. Harnessing NKT cells for vaccination.Oxford open immunology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 4 countries.

Jing HuangAaron Diamond AIDS Research Center, The Rockefeller University, New York, NY, United States.
Jing ZhouIsoPlexis, Branford, CT, United States.
Reem GhinnagowCentre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, CHU Lille, Institut Pasteur de Lille, University of Lille, Lille, France.
Toshiyuki SekiAaron Diamond AIDS Research Center, The Rockefeller University, New York, NY, United States.
Sho IketaniAaron Diamond AIDS Research Center, The Rockefeller University, New York, NY, United States.
Daphnée SoulardCentre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, CHU Lille, Institut Pasteur de Lille, University of Lille, Lille, France.
Patrick PaczkowskiIsoPlexis, Branford, CT, United States.
Yukiko TsujiAaron Diamond AIDS Research Center, The Rockefeller University, New York, NY, United States.
Sean MacKayIsoPlexis, Branford, CT, United States.
Luis Javier CruzTranslational Nanobiomaterials and Imaging, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands.
François TrotteinCentre d'Infection et d'Immunité de Lille, Inserm U1019, CNRS UMR 8204, CHU Lille, Institut Pasteur de Lille, University of Lille, Lille, France.
Moriya TsujiAaron Diamond AIDS Research Center, The Rockefeller University, New York, NY, United States.
IsoPlexis (United States) · USRockefeller University · USAaron Diamond AIDS Research Center · USCentre National de la Recherche Scientifique · FRColumbia University Irving Medical Center · USInstitut Pasteur de Lille · FRJikei University School of Medicine · JPLeiden University Medical Center · NLUniversité de Lille · FR

Funding

CD1d/NKT-binding glycolipids in enhancing the immunogenicity of a malaria vaccineR01AI070258 · NIAID · AARON DIAMOND AIDS RESEARCH CENTER · PI TSUJI, MORIYA · 2012 to 2016
$2.2M
A single-cell mouse proteomic system to accelerate pre-clinical immune therapeuticsR44OD021445 · OD · ISOPLEXIS, INC. · PI MCCONNELL, TIMOTHY S, ZHOU, JING · 2017 to 2019
$1.8M
Single-cell multi-protein device for informative cellular function evaluationR43OD021445 · OD · ISOPLEXIS, INC. · PI MCCONNELL, TIMOTHY S · 2016 to 2016
$164k
NIAID NIH HHS R01 AI070258NIH HHS R43 OD021445NIH HHS R44 OD021445
6 · The paper itself

Abstract

Active co-delivery of tumor antigens (Ag) and α-galactosylceramide (α-GalCer), a potent agonist for invariant Natural Killer T (

Indexed as

AnimalsAntigens, NeoplasmBiomarkersCancer VaccinesCD8-Positive T-LymphocytesDendritic CellsEpitopes, T-LymphocyteGalactosylceramidesHumansImmunophenotypingLectins, C-TypeMiceMice, Inbred NODMice, TransgenicProteomicsReceptors, Mitogenalpha-galactosylceramideAntigens, NeoplasmBiomarkersCancer VaccinesCLEC9a protein, humanEpitopes, T-LymphocyteGalactosylceramidesLectins, C-TypeReceptors, MitogenTHBD protein, humanThrombomodulinCD8+ T cellshuman CD141+ DCshuman immune system miceiNKT cellsmelanomananovaccinetargetingα-galactosylceramide

Identifiers

PMID32973811
PMCPMC7461784
OpenAlexW3054921167

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.