Evidence map›Paper›PMID 32973787›Full record

ArticleFrontiers in immunology2020

Altered Levels of Decidual Immune Cell Subsets in Fetal Growth Restriction, Stillbirth, and Placental Pathology.

Romy E Bezemer, Mirthe H Schoots, Albertus Timmer, Sicco A Scherjon, Jan Jaap H M Erwich, Harry van Goor, Sanne J Gordijn, Jelmer R Prins

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 54 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Romy E BezemerDepartment of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Mirthe H SchootsDivision of Pathology, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Albertus TimmerDivision of Pathology, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Sicco A ScherjonDepartment of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Jan Jaap H M ErwichDepartment of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Harry van GoorDivision of Pathology, Department of Pathology and Medical Biology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Sanne J GordijnDepartment of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
Jelmer R PrinsDepartment of Obstetrics and Gynecology, University Medical Center Groningen, University of Groningen, Groningen, Netherlands.
University of Groningen · NLUniversity Medical Center Groningen · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immune cells are critically involved in placental development and functioning, and inadequate regulation of the maternal immune system is associated with placental pathology and pregnancy complications. This study aimed to explore numbers of decidual immune cells in pregnancies complicated with fetal growth restriction (FGR) and stillbirth (SB), and in placentas with histopathological lesions: maternal vascular malperfusion (MVM), fetal vascular malperfusion (FVM), delayed villous maturation (DVM), chorioamnionitis (CA), and villitis of unknown etiology (VUE). Placental tissue from FGR (

Indexed as

StillbirthAdultBiomarkersCase-Control StudiesDeciduaFemaleFetal Growth RetardationHistocompatibility, Maternal-FetalHumansImmunohistochemistryImmunophenotypingKiller Cells, NaturalMacrophagesMalePhenotypePlacentaBiomarkersfetal growth restrictionmacrophagenatural killer cellplacental pathologypregnancyregulatory T cellstillbirth

Identifiers

PMID32973787
PMCPMC7468421
OpenAlexW3080629327

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.