Evidence map›Paper›PMID 32973748›Full record

ArticleFrontiers in immunology2020

Myeloid-Derived Suppressor Cells Promote the Progression of Primary Membranous Nephropathy by Enhancing Th17 Response.

Huimin Li, Hao Wu, Qiaoyan Guo, Hongyu Yu, Ying Xu, Jinyu Yu, Zhongkun Wang, Huanfa Yi

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 25 citations in OpenAlex.

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  12. Polyamines from myeloid-derived suppressor cells promote Th17 polarization and disease progression.Molecular therapy : the journal of the American Society of Gene Therapy · 2023
    Article
  13. Article
  14. Toxic Occupational Exposures and Membranous Nephropathy.Clinical journal of the American Society of Nephrology : CJASN · 2022
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Huimin LiCentral Laboratory, The First Hospital of Jilin University, Changchun, China.
Hao WuDepartment of Nephrology, The First Hospital of Jilin University, Changchun, China.
Qiaoyan GuoDepartment of Nephrology, The Second Hospital of Jilin University, Changchun, China.
Hongyu YuDepartment of Nephrology, The Second Hospital of Jilin University, Changchun, China.
Ying XuDepartment of Nephrology, The First Hospital of Jilin University, Changchun, China.
Jinyu YuDepartment of Nephrology, The First Hospital of Jilin University, Changchun, China.
Zhongkun WangCentral Laboratory, The First Hospital of Jilin University, Changchun, China.
Huanfa YiCentral Laboratory, The First Hospital of Jilin University, Changchun, China.
First Hospital of Jilin University · CNJilin University · CNMinistry of Education of the People's Republic of China · CNSecond Affiliated Hospital of Jilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Several studies have confirmed that the myeloid-derived suppressor cells (MDSCs) are closely associated with autoimmune diseases, but their exact role in these processes remains largely unclear. Here, we investigated the role MDSCs in patients with primary membranous nephropathy (PMN). Compared to healthy controls (HCs), PMN patients showed significantly increased number of HLA-DR

Indexed as

Cell CommunicationArginaseAutoantibodiesCase-Control StudiesCell DifferentiationCytokinesDisease ProgressionGlomerulonephritis, MembranousHumansKidney GlomerulusMyeloid-Derived Suppressor CellsReceptors, Phospholipase A2Signal TransductionTh17 CellsTh2 CellsARG1 protein, humanArginaseAutoantibodiesCytokinesPLA2R1 protein, humanReceptors, Phospholipase A2arginase-1myeloid-derived suppressor cellsprimary membranous nephropathyT helper 17T helper 2

Identifiers

PMID32973748
PMCPMC7468481
OpenAlexW3080599187

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.