Evidence map›Paper›PMID 32973740›Full record

ArticleFrontiers in immunology2020

Cyclic Peptide [R

Joshua Hernandez, David Ashley, Ruoqiong Cao, Rachel Abrahem, Timothy Nguyen, Kimberly To, Aram Yegiazaryan, Ajayi Akinwale David, Rakesh Kumar Tiwari, Vishwanath Venketaraman

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Additive Effects ofInternational journal of molecular sciences · 2025
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Combination of Amphiphilic Cyclic Peptide [RAntibiotics (Basel, Switzerland) · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Joshua HernandezGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
David AshleyGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Ruoqiong CaoDepartment of Basic Medical Sciences, College of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, United States.
Rachel AbrahemGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Timothy NguyenCollege of Osteopathic Medicine of the Pacific, Western University of Health Sciences, Pomona, CA, United States.
Kimberly ToGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Aram YegiazaryanGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Ajayi Akinwale DavidDepartment of Biomedical and Pharmaceutical Sciences, Center for Targeted Drug Delivery, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, CA, United States.
Rakesh Kumar TiwariDepartment of Biomedical and Pharmaceutical Sciences, Center for Targeted Drug Delivery, Chapman University School of Pharmacy, Harry and Diane Rinker Health Science Campus, Irvine, CA, United States.
Vishwanath VenketaramanGraduate College of Biomedical Sciences, Western University of Health Sciences, Pomona, CA, United States.
Western University of Health Sciences · USChapman University · USTarget (United States) · US

Funding

Glutathione depletion in the CNS and its effects on Mtb infectionR15HL143545 · NHLBI · WESTERN UNIVERSITY OF HEALTH SCIENCES · PI VENKETARAMAN, VISHWANATH · 2019 to 2024
$852k
NHLBI NIH HHS R15 HL143545
6 · The paper itself

Abstract

Tuberculosis (TB) is currently one of the leading causes of global mortality. Medical non-compliance due to the length of the treatment and antibiotic side effects has led to the emergence of multidrug-resistant (MDR) strains of

Indexed as

AdolescentAdultAgedAntibiotics, AntitubercularAutophagyCytokinesDrug Therapy, CombinationGranulomaHost-Pathogen InteractionsHumansIsoniazidMicrobial ViabilityMiddle AgedMycobacterium tuberculosisOxidative StressPeptides, CyclicAntibiotics, Antitubercularcyclic peptide R4W4CytokinesIsoniazidPeptides, CyclicPyrazinamideantimicrobial peptidescyclic peptidecytokinehost–bacteria interactiontuberculosis

Identifiers

PMID32973740
PMCPMC7438584
OpenAlexW3048366075

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.