Evidence map›Paper›PMID 32973682›Full record

ReviewFrontiers in endocrinology2020

Role of the PD-1/PD-L1 Dyad in the Maintenance of Pancreatic Immune Tolerance for Prevention of Type 1 Diabetes.

Marika Falcone, Georgia Fousteri

Abstract readReview
In one paragraph

Review in Frontiers in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Marika FalconeDivision of Immunology, Transplantation, and Infectious Diseases, San Raffaele Scientific Institute, DRI - Diabetes Research Institute, Regulation of Adaptive Immunology, Milan, Italy.
Georgia FousteriDivision of Immunology, Transplantation, and Infectious Diseases, San Raffaele Scientific Institute, DRI - Diabetes Research Institute, Regulation of Adaptive Immunology, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The human pancreas, like almost all organs in the human body, is immunologically tolerated despite the presence of innate and adaptive immune cells that promptly mediate protective immune responses against pathogens

Indexed as

B7-H1 AntigenDiabetes Mellitus, Type 1HumansImmune TolerancePancreasProgrammed Cell Death 1 ReceptorB7-H1 AntigenProgrammed Cell Death 1 Receptorimmune homeostasisimmune toleranceimmunotherapypancreaspancreatic islet transplantationprogrammed death 1 (PD-1)programmed death ligand 1 (PD-L1)type 1 diabetes (T1D)

Identifiers

PMID32973682
PMCPMC7466754

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.