Evidence map›Paper›PMID 32973567›Full record

ArticleFrontiers in physiology2020

Potential Application of Human β-Defensin 4 in Dental Pulp Repair.

Yue Zhai, Xiaojing Yuan, Yuming Zhao, Lihong Ge, Yuanyuan Wang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Review
  4. Article
  5. Review
  6. International journal of molecular sciences · 2025
    Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. The effect of BMP9 on inflammation in the early stage of pulpitis.Journal of applied oral science : revista FOB · 2023
    Article
  15. Article
  16. Review
  17. Dental-Derived Mesenchymal Stem Cells: State of the Art.Frontiers in cell and developmental biology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Yue ZhaiDepartment of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Xiaojing YuanDepartment of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Yuming ZhaoDepartment of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Lihong GeDepartment of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Yuanyuan WangDepartment of Pediatric Dentistry, Peking University School and Hospital of Stomatology, Beijing, China.
Peking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

When pulp tissue is damaged by caries or trauma, vital pulp therapy (VPT) can help preserve the pulp tissue for long-term retention of teeth. However, the choice of pulp capping agent used in VPT is important for the successful preservation of the pulp tissue. Here we investigated the expression and biological function of human β-defensin 4 (HBD4) in dental pulp stem cells (DPSC) and explored its potential as a pulp capping agent. We examined the expression of HBD4 in DPSC

Indexed as

anti-inflammatorydental pulp stem cellshuman β-defensin 4stem cell differentiationvital pulp therapy

Identifiers

PMID32973567
PMCPMC7472722
OpenAlexW3080587041

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.