Evidence map›Paper›PMID 32973515›Full record

ArticleFrontiers in pharmacology2020

FOXD3-AS1 Knockdown Suppresses Hypoxia-Induced Cardiomyocyte Injury by Increasing Cell Survival and Inhibiting Apoptosis

Jiayong Zheng, Bangtian Peng, Yanwei Zhang, Feng Ai, Xiaosong Hu

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jiayong ZhengDepartment of Children's Heart Center, Henan Province People's Hospital, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Bangtian PengDepartment of Children's Heart Center, Henan Province People's Hospital, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Yanwei ZhangDepartment of Children's Heart Center, Henan Province People's Hospital, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Feng AiDepartment of Children's Heart Center, Henan Province People's Hospital, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.
Xiaosong HuDepartment of Children's Heart Center, Henan Province People's Hospital, Fuwai Central China Cardiovascular Hospital, Zhengzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Congenital heart disease (CHD) is the most common type of human innate malformation in fetuses. LncRNAs have been pointed to play critical regulatory roles in various types of cardiac development and diseases including CHD. Our study aimed to explore the effects of lncRNA forkhead box D3 antisense RNA 1 (FOXD3-AS1) on hypoxia-induced injury in AC16 cardiomyocytes and the related molecular mechanism.

Indexed as

apoptosiscardiomyocytecongenital heart diseaseFOXD3-AS1hypoxiamiR-150-5p

Identifiers

PMID32973515
PMCPMC7469905

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.