ArticleScientific reports2020
Metagenomic analysis of human-biting cat fleas in urban northeastern United States of America reveals an emerging zoonotic pathogen.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
11 citing papers in PubMed.
- Identification of Ctenocephalides felis felis and the detection and characterization of associated Wolbachia endosymbiont in Pakistan.BMC veterinary research · 2026Article
- The First Report on Cat Flea (Ctenocephalides felis), a Zoonotic Haematophagous Insect Infestation in Humans in Bangladesh: A Case Report and Literature Review.Veterinary medicine and science · 2025Review
- Dog ectoparasites as sentinels for pathogenic Rickettsia and Bartonella in rural Guatemala.Acta tropica · 2024Article
- Dog ectoparasites as sentinels for pathogenic Rickettsia and Bartonella in rural Guatemala.Research square · 2024Article
- Vector biology of the cat flea Ctenocephalides felis.Trends in parasitology · 2024Review
- Metagenomics of culture isolates and insect tissue illuminate the evolution ofMicrobial genomics · 2023Article
- Identification of microbial taxa present in Ctenocephalides felis (cat flea) reveals widespread co-infection and associations with vector phylogeny.Parasites & vectors · 2022Article
- Visual closed dumbbell-mediated isothermal amplification (CDA) for on-site detection of Rickettsia raoultii.PLoS neglected tropical diseases · 2022Article
- Development of a Multiplex Droplet Digital PCR Assay for the Detection ofPathogens (Basel, Switzerland) · 2021Article
- Unpacking the intricacies of Rickettsia-vector interactions.Trends in parasitology · 2021Review
- Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
An infestation of cat fleas in a research center led to the detection of two genotypes of Ctenocephalides felis biting humans in New Jersey, USA. The rarer flea genotype had an 83% incidence of Rickettsia asembonensis, a recently described bacterium closely related to R. felis, a known human pathogen. A metagenomics analysis developed in under a week recovered the entire R. asembonensis genome at high coverage and matched it to identical or almost identical (> 99% similarity) strains reported worldwide. Our study exposes the potential of cat fleas as vectors of human pathogens in crowded northeastern U.S, cities and suburbs where free-ranging cats are abundant. Furthermore, it demonstrates the power of metagenomics to glean large amounts of comparative data regarding both emerging vectors and their pathogens.
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Registered trials
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