Evidence map›Paper›PMID 32973295›Full record

ArticleScientific reports2020

Chemical composition and antimicrobial activity of essential oils obtained from leaves and flowers of Salvia hydrangea DC. ex Benth.

Mansureh Ghavam, Maria Letizia Manca, Maria Manconi, Gianluigi Bacchetta

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
11.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 100 citations in OpenAlex.

  1. Review
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  3. Phytochemical Profiling and Antioxidant Activity ofPharmaceuticals (Basel, Switzerland) · 2026
    Article
  4. A Review of Essential Oils with Anti-Foods (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
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  14. Article
  15. Article
  16. Article
  17. Review
  18. Antimicrobial potential of IndianSaudi journal of biological sciences · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Mansureh GhavamDepartment of Range and Watershed Management, Faculty of Natural Resources and Earth Sciences, University of Kashan, Kashan, Iran. mghavam@kashanu.ac.ir.ORCID http://orcid.org/0000-0002-8078-8664
Maria Letizia MancaDepartment Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.ORCID http://orcid.org/0000-0002-3787-257X
Maria ManconiDepartment Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
Gianluigi BacchettaDepartment Life and Environmental Sciences, University of Cagliari, Cagliari, Italy.
University of Cagliari · ITUniversity of Kashan · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The majority of essential oils obtained from vascular plants have been demonstrated to be effective in treating fungal and bacterial infections. Among others, Salvia hydrangea is an endemic half-shrub belonging to the Lamiaceae family that has been widely used from ancient times in Iranian traditional medicine. The aim of this study was to compare the composition and antimicrobial properties of essential oils obtained from leaves or flowers of this plant, collected from the Daran region of Iran during June 2018. The oils were obtained using Clevenger apparatus, their composition was evaluated by means of gas chromatography/mass spectrometry (GC/MS) and the antimicrobial properties were assayed by measuring inhibition halos, minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC). The yield of leaf oil was ~ 0.25% and that of flower oil was ~ 0.28%. Oil composition was affected by the part of the plants used: the most abundant bioactives contained in leaf essential oil were (+)-spathulenol (16.07%), 1,8-cineole (13.96%), trans-caryophyllene (9.58%), β-pinene (8.91%) and β-eudesmol (5.33%) and those in flower essential oil were caryophyllene oxide (35.47%), 1,8-cineole (9.54%), trans-caryophyllene (6.36%), β-eudesmol (4.11%), caryophyllenol-II (3.46%) and camphor (3.33%). Both the oils showed a significant inhibitory and lethal effect on the Gram-negative bacteria Pseudomonas aeruginosa (MIC ~ 16 µg/mL), Shigella dysenteriae and Klebsiella pneumoniae (MIC ~ 62 µg/mL). Therefore, the essential oils obtained from both leaves and flowers of S. hydrangea may have potential application as bactericidal agents against some bacteria.

Indexed as

Anti-Infective AgentsFlowersMicrobial Sensitivity TestsOils, VolatilePlant LeavesSalviaAnti-Infective AgentsOils, Volatile

Identifiers

PMID32973295
PMCPMC7519093
OpenAlexW3088263409

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.