Evidence map›Paper›PMID 32973252›Full record

ArticleScientific reports2020

A dichoptic feedback-based oculomotor training method to manipulate interocular alignment.

Andrea Caoli, Silvio P Sabatini, Agostino Gibaldi, Guido Maiello, Anna Kosovicheva, Peter Bex

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 3 countries.

Andrea CaoliDepartment of Psychology, Northeastern University, Boston, MA, 02115, USA.
Silvio P SabatiniDepartment of Informatics, Bioengineering, Robotics and System Engineering-DIBRIS, University of Genoa, Via all'Opera Pia 13, 16145, Genoa, Italy.
Agostino GibaldiSchool of Optometry and Vision Science, University of California at Berkeley, Berkeley, CA, 94720, USA.
Guido MaielloDepartment of Experimental Psychology, Justus Liebig University Giessen, 35394, Giessen, Germany.
Anna KosovichevaDepartment of Psychology, Northeastern University, Boston, MA, 02115, USA.
Peter BexDepartment of Psychology, Northeastern University, Boston, MA, 02115, USA. p.bex@neu.edu.
Northeastern University · USUniversity of Genoa · ITUniversity of California, Berkeley · USUniversity of Giessen · DE

Funding

Eye Movement Rehabilitation in Low Vision PatientsR01EY029713 · NEI · NORTHEASTERN UNIVERSITY · PI BEX, PETER JOHN · 2019 to 2023
$1.9M
Oculomotor deficits and plasticity across gaze posture in strabismusF32EY028814 · NEI · NORTHEASTERN UNIVERSITY · PI KOSOVICHEVA, ANNA · 2018 to 2020
$189k
Marie Curie 793660NEI NIH HHS F32 EY028814NEI NIH HHS R01 EY029713NIH HHS F32 EY028814NIH HHS R01 EY029713
6 · The paper itself

Abstract

Strabismus is a prevalent impairment of binocular alignment that is associated with a spectrum of perceptual deficits and social disadvantages. Current treatments for strabismus involve ocular alignment through surgical or optical methods and may include vision therapy exercises. In the present study, we explore the potential of real-time dichoptic visual feedback that may be used to quantify and manipulate interocular alignment. A gaze-contingent ring was presented independently to each eye of 11 normally-sighted observers as they fixated a target dot presented only to their dominant eye. Their task was to center the rings within 2° of the target for at least 1 s, with feedback provided by the sizes of the rings. By offsetting the ring in the non-dominant eye temporally or nasally, this task required convergence or divergence, respectively, of the non-dominant eye. Eight of 11 observers attained 5° asymmetric convergence and 3 of 11 attained 3° asymmetric divergence. The results suggest that real-time gaze-contingent feedback may be used to quantify and transiently simulate strabismus and holds promise as a method to augment existing therapies for oculomotor alignment disorders.

Indexed as

FeedbackSensory ThresholdsContrast SensitivityEye MovementsFemaleHumansMaleOculomotor MusclesPhotic StimulationStrabismusTask Performance and AnalysisVision, BinocularVisual AcuityVisual Perception

Identifiers

PMID32973252
PMCPMC7515870
OpenAlexW3089035424

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.