ArticleScientific reports2020
Changes in performance and bio-mathematical model performance predictions during 45 days of sleep restriction in a simulated space mission.
Article in Scientific reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 30 citations in OpenAlex.
- Pilot feasibility testing of biomathematical model recommendations for personalising sleep timing in shift workers.Journal of sleep research · 2025Article
- Circadian Disruption and Sleep Disorders in Astronauts: A Review of Multi-Disciplinary Interventions for Long-Duration Space Missions.International journal of molecular sciences · 2025Review
- taVNS as a potential countermeasure for neurocognitive decline in microgravity.Frontiers in neuroscience · 2025Article
- Simulating microgravity with 60 days of 6 degree head-down tilt bed rest compromises sleep.NPJ microgravity · 2024Article
- Biomathematical modeling of fatigue due to sleep inertia.Journal of theoretical biology · 2024Article
- The effect of a dynamic lighting schedule on neurobehavioral performance during a 45-day simulated space mission.Sleep advances : a journal of the Sleep Research Society · 2024Article
- Article
- Effects of dynamic lighting on circadian phase, self-reported sleep and performance during a 45-day space analog mission with chronic variable sleep deficiency.Journal of pineal research · 2022Article
- Cortical waste clearance in normal and restricted sleep with potential runaway tau buildup in Alzheimer's disease.Scientific reports · 2022Article
- Sleep, time, and space-fatigue and performance deficits in pilots, commercial truck drivers, and astronauts.Sleep advances : a journal of the Sleep Research Society · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 4 institutions in 2 countries.
Funding
Abstract
Lunar habitation and exploration of space beyond low-Earth orbit will require small crews to live in isolation and confinement while maintaining a high level of performance with limited support from mission control. Astronauts only achieve approximately 6 h of sleep per night, but few studies have linked sleep deficiency in space to performance impairment. We studied crewmembers over 45 days during a simulated space mission that included 5 h of sleep opportunity on weekdays and 8 h of sleep on weekends to characterize changes in performance on the psychomotor vigilance task (PVT) and subjective fatigue ratings. We further evaluated how well bio-mathematical models designed to predict performance changes due to sleep loss compared to objective performance. We studied 20 individuals during five missions and found that objective performance, but not subjective fatigue, declined from the beginning to the end of the mission. We found that bio-mathematical models were able to predict average changes across the mission but were less sensitive at predicting individual-level performance. Our findings suggest that sleep should be prioritized in lunar crews to minimize the potential for performance errors. Bio-mathematical models may be useful for aiding crews in schedule design but not for individual-level fitness-for-duty decisions.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.