ArticleRespiratory care2020
Ventilator Liberation in the Pediatric ICU.
Article in Respiratory care, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 4 syntheses or guidelines pooled it.
- Diaphragmatic Ultrasonography as a Predictor of Extubation Success in Children: Systematic Review and Meta-Analysis.Pediatric pulmonology · 2026Pooled it
- Automated versus non-automated weaning for reducing the duration of mechanical ventilation for critically ill adults and children.The Cochrane database of systematic reviews · 2025Pooled it
- Guideline
- Executive Summary: International Clinical Practice Guidelines for Pediatric Ventilator Liberation, A Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Document.American journal of respiratory and critical care medicine · 2023Pooled it
- Surface electromyography to quantify neuro-respiratory drive and neuro-mechanical coupling in mechanically ventilated children.Respiratory research · 2023Trial
- Trial
- Diaphragm ultrasound parameters and rapid shallow breathing index for predicting weaning failure in mechanically ventilated infants: a prospective observational PICU study.European journal of pediatrics · 2026Observational
- Postextubation Arterial Blood Gas to Predict Reintubation in Children With Congenital Heart Disease.Respiratory care · 2026Article
- Predictive Analysis of Extubation Failure in the Paediatric Intensive Care Unit in Bloemfontein, South Africa.Reports (MDPI) · 2026Article
- Risk Factors and Clinical Outcomes of Post-Extubation Stridor in Pediatric Intensive Care.Children (Basel, Switzerland) · 2025Article
- Expert-augmented machine learning for predicting extubation readiness in the pediatric intensive care unit.BMC medical informatics and decision making · 2025Article
- Value of combining lung ultrasound score with oxygenation and functional indices in determining weaning timing for critically ill pediatric patients.BMC medical imaging · 2025Article
- The Decision to Extubate: The Association between Clinician Impressions and Objective Extubation Readiness Criteria in a Pediatric Intensive Care Unit.Journal of pediatric intensive care · 2024Article
- Factors Associated With Successful Extubation Readiness Testing in Children With Congenital Heart Disease.Respiratory care · 2024Article
- Ventilation liberation in Ibero-American pediatric intensive care units.Critical care science · 2024Article
- Clinical practices related to liberation from mechanical ventilation in Latin American pediatric intensive care units: survey of the Sociedad Latino-Americana de Cuidados Intensivos Pediátricos Mechanical Ventilation Liberation Group.Critical care science · 2024Article
- Fitness checklist model for spontaneous breathing tests in pediatrics.Critical care science · 2023Article
- Tests and Indices Predicting Extubation Failure in Children: A Systematic Review and Meta-analysis.Pulmonary therapy · 2023Review
- Association Between Pressure Support During Extubation Readiness Testing and Time to First Extubation in Children With Congenital Heart Disease.Respiratory care · 2023Article
- Pediatric ventilation liberation: evaluating the role of endotracheal secretions in an extubation readiness bundle.Pediatric research · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
Despite the accepted importance of minimizing time on mechanical ventilation, only limited guidance on weaning and extubation is available from the pediatric literature. A significant proportion of patients being evaluated for weaning are actually ready for extubation, suggesting that weaning is often not considered early enough in the course of ventilation. Indications for extubation are often not clear, although a trial of spontaneous breathing on CPAP without pressure support seems an appropriate prerequisite in many cases. Several indexes have been developed to predict weaning and extubation success, but the available literature suggests they offer little or no improvement over clinical judgment. New techniques for assessing readiness for weaning and predicting extubation success are being developed but are far from general acceptance in pediatric practice. While there have been some excellent physiologic, observational, and even randomized controlled trials on aspects of pediatric ventilator liberation, robust research data are lacking. Given the lack of data in many areas, a determined approach that combines systematic review with consensus opinion of international experts could generate high-quality recommendations and terminology definitions to guide clinical practice and highlight important areas for future research in weaning, extubation readiness, and liberation from mechanical ventilation following pediatric respiratory failure.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.