Evidence map›Paper›PMID 32973095›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2020

Alternative proton-binding site and long-distance coupling in

Jack A Henderson, Yandong Huang, Oliver Beckstein, Jana Shen

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. pH-dependent activation of the NaNature communications · 2026
    Article
  3. Article
  4. Conduction pathway for potassium through the E. coli pump KdpFABC.bioRxiv : the preprint server for biology · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Crystal structure of the NaNature communications · 2022
    Article
  14. Prokaryotic NaInternational journal of molecular sciences · 2022
    Review
  15. Article
  16. Protein pACS omega · 2021
    Article
  17. Article
  18. How μ-opioid receptor recognizes fentanyl.Nature communications · 2021
    Article
  19. HowbioRxiv : the preprint server for biology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jack A HendersonDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201.ORCID 0000-0001-6675-7944
Yandong HuangCollege of Computer Engineering, Jimei University, Xiamen 361021, Fujian Province, China.ORCID 0000-0002-1452-6383
Oliver BecksteinDepartment of Physics, Arizona State University, Tempe, AZ 85287.ORCID 0000-0003-1340-0831
Jana ShenDepartment of Pharmaceutical Sciences, University of Maryland School of Pharmacy, Baltimore, MD 21201; jana.shen@rx.umaryland.edu.ORCID 0000-0002-3234-0769

Funding

Electrostatic modulation of protein stability and foldingR01GM098818 · NIGMS · UNIVERSITY OF OKLAHOMA · PI SHEN, JANA · 2011 to 2021
$2.9M
Molecular mechanisms of secondary active transportersR01GM118772 · NIGMS · ARIZONA STATE UNIVERSITY-TEMPE CAMPUS · PI BECKSTEIN, OLIVER · 2016 to 2020
$1.5M
NIGMS NIH HHS R01 GM098818NIGMS NIH HHS R01 GM118772
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Escherichia coli ProteinsProtonsSodium-Hydrogen ExchangersAspartic AcidBinding SitesHydrogen BondingLysineMolecular Dynamics SimulationMutationStatic ElectricityAspartic AcidEscherichia coli ProteinsLysineNhaA protein, E coliProtonsSodium-Hydrogen Exchangerscation–proton antiportersmolecular dynamicsprotein electrostaticsproton transportsecondary active transporters

Identifiers

PMID32973095
PMCPMC7568328

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.