Evidence map›Paper›PMID 32973079›Full record

ArticleBiology open2020

The Rab11 effectors Fip5 and Fip1 regulate zebrafish intestinal development.

Cayla E Jewett, Bruce H Appel, Rytis Prekeris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biology open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Cayla E JewettDepartment of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, CO 80045, USA.ORCID 0000-0002-8406-0814
Bruce H AppelDepartment of Pediatrics, University of Colorado School of Medicine, Aurora, CO 80045, USA.ORCID 0000-0003-4500-0672
Rytis PrekerisDepartment of Cell and Developmental Biology, University of Colorado School of Medicine, Aurora, CO 80045, USA Rytis.Prekeris@cuanschutz.edu.ORCID 0000-0003-3393-1963
University of Colorado Denver · US

Funding

Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and CiliogenesisR01DK064380 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Rytis Prekeris · 2004 to 2026
$7.1M
Predoctoral Training Program in Molecular and Cellular Biology (Supplement: Mentoring in the Research Environment)T32GM136444 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI MICHAEL A MCMURRAY, Rytis Prekeris · 2020 to 2026
$3.7M
Predoctoral Training Program in Molecular BiologyT32GM008730 · NIGMS · UNIVERSITY OF COLORADO DENVER · PI PREKERIS, RYTIS, SCLAFANI, ROBERT A · 1999 to 2019
$3.3M
NIDDK NIH HHS R01 DK064380NIGMS NIH HHS T32 GM008730NIGMS NIH HHS T32 GM136444
6 · The paper itself

Abstract

The Rab11 apical recycling endosome pathway is a well-established regulator of polarity and lumen formation; however, Rab11-vesicular trafficking also directs a diverse array of other cellular processes, raising the question of how Rab11 vesicles achieve specificity in space, time and content of cargo delivery. In part, this specificity is achieved through effector proteins, yet the role of Rab11 effector proteins

Indexed as

AnimalsCarrier ProteinsEndosomesIntestinesMicrovilliMutationOrganogenesisPhenotypeProtein Bindingrab11 GTP-Binding Proteinsrab GTP-Binding ProteinsZebrafishCarrier Proteinsrab11 GTP-Binding Proteinsrab GTP-Binding ProteinsFIP1FIP5MicrovilliRab11RCPRip11

Identifiers

PMID32973079
PMCPMC7595698
OpenAlexW3088409692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.