ArticleBMJ open2020
Nationwide incidence of central retinal artery occlusion in Japan: an exploratory descriptive study using the National Database of Health Insurance Claims (2011-2015).
Article in BMJ open, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
30 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Interventions for acute non-arteritic central retinal artery occlusion.The Cochrane database of systematic reviews · 2023Pooled it
- Intravenous thrombolysis in patients with central retinal artery occlusion: a systematic review and meta-analysis.Journal of neurology · 2022Pooled it
- Nationwide epidemiology of retinitis pigmentosa in Japan, 2011-2020: a population-based cohort study.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Global research trends in central retinal artery occlusion: a bibliometric analysis (1980-2025).International ophthalmology · 2026Review
- Effectiveness and safety of superselective ophthalmic artery thrombolysis beyond 24h in central retinal artery occlusion.International journal of ophthalmology · 2026Article
- Safety and Efficacy of Orally Administered SJP-0008 in Central Retinal Artery Occlusion: A Phase IIa Randomized Clinical Trial.Ophthalmology science · 2026Article
- Central Retinal Artery Occlusion in the Emergency Department: A Case Report of Prompt Diagnosis and Treatment.Cureus · 2025Article
- RNF213 c.14429G > A (p.Arg4810Lys) is associated with non-arteritic retinal artery occlusion.Scientific reports · 2025Article
- Central Retinal Artery Occlusion in Acute Care: Current Practices and Emerging Therapies.Cureus · 2025Review
- Lifetime risk, sex and age differences in annual incidence of ocular motor cranial nerve palsy in Japan for 2019.Communications medicine · 2025Article
- Antithrombotic use in retinal artery occlusion: A narrative review.The Kaohsiung journal of medical sciences · 2025Review
- Ankle-Brachial Index as a Predictor of Acute Ischemic Cerebrovascular Event After Central Retinal Artery Occlusion.Medical science monitor : international medical journal of experimental and clinical research · 2025Article
- Central retinal artery occlusion: a stroke of the eye.Eye (London, England) · 2024Review
- Real-World Research on Retinal Diseases Using Health Claims Database: A Narrative Review.Diagnostics (Basel, Switzerland) · 2024Review
- National trends in hospitalizations for gastrointestinal bleeding in Japan.Journal of clinical biochemistry and nutrition · 2024Article
- Literature Review of Studies Using the National Database of the Health Insurance Claims of Japan (NDB): Limitations and Strategies in Using the NDB for Research.JMA journal · 2024Review
- Visual acuity improvement after treatment of central retinal artery occlusion: a case report.The Pan African medical journal · 2024Article
- Annual trends of ophthalmic surgeries in Japan's super-aged society, 2014-2020: a national claims database study.Scientific reports · 2023Article
- Statin Treatment on Cardiovascular Risk After Retinal Artery Occlusion: A Historical Cohort Study.Journal of epidemiology and global health · 2023Article
- Progress in central retinal artery occlusion: a narrative review.The Journal of international medical research · 2023Review
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimsThe latest evidence in the incidence of central retinal artery occlusion (CRAO) is needed to support the development of novel treatments as orphan drugs. However, up-to-date information on the incidence of CRAO in the ageing or aged population is limited. We aimed to investigate the nationwide epidemiological and clinical characteristics of CRAO in Japan, using nationwide health insurance claims data.
methodsWe analysed a total of 16 069 762 claims data in the sampling dataset of the National Database of Health Insurance Claims and Specific Health Checkups of Japan (NDB), which is the nationwide health insurance claims database of 127 million whole Japanese individuals. CRAO was identified using the International Classification of Diseases 10th edition diagnostic code H34.1. The crude incidence rates and age-standardised incidence rates of CRAO, according to the standard age-structure population of the WHO, were calculated.
resultsThe crude incidence rate of CRAO in Japan was 5.84 (95% CI, 5.71 to 5.97) per 100 000 person-years. With respect to the sex-related incidence, the rate was higher 1.40 times in men than in women (6.85 (95% CI, 6.65 to 7.06) vs 4.88 (95% CI, 4.71 to 5.05), p<0.001). The age-standardised incidence rate was 2.53 (95% CI, 2.29 to 2.76) per 100 000 person-years.
conclusionsThe crude incidence rate of CRAO was higher in Japan than in other countries, as reported previously, reflecting the Japanese population structure as a super-aged society. These findings can be helpful for the development of appropriate healthcare policies to address the increasing incidence of CRAO with the ageing population.
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