Evidence map›Paper›PMID 32972777›Full record

ArticleJournal of the American Society of Echocardiography : official publication of the American Society of Echocardiography2020

Improved Delineation of Cardiac Pathology Using a Novel Three-Dimensional Echocardiographic Tissue Transparency Tool.

Ilya Karagodin, Karima Addetia, Amita Singh, Alasdair Dow, Lydia Rivera, Jeanne M DeCara, Laurie Soulat-Dufour, Megan Yamat, Eric Kruse, Atman P Shah and 2 more

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Unveiling the Marvels of 3D Echo:Sultan Qaboos University medical journal · 2025
    Article
  3. Review
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  7. The effects of leaflet material properties on the simulated function of regurgitant mitral valves.Journal of the mechanical behavior of biomedical materials · 2023
    Article
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  13. Article
  14. Unearthing the Tunnel.JACC. Case reports · 2022
    Article
  15. 3D echocardiography in mitral valve prolapse.Frontiers in cardiovascular medicine · 2022
    Review
  16. Utility of transillumination and transparency renderings in 3D transthoracic imaging.The international journal of cardiovascular imaging · 2022
    Article
  17. Review
  18. Article
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  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Ilya KaragodinSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Karima AddetiaSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Amita SinghSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Alasdair DowPhilips Medical Systems, Amsterdam, Netherlands.
Lydia RiveraPhilips Medical Systems, Amsterdam, Netherlands.
Jeanne M DeCaraSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Laurie Soulat-DufourSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois; Sorbonne University, APHP, Paris, France.
Megan YamatSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Eric KruseSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Atman P ShahSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Victor Mor-AviSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois.
Roberto M LangSection of Cardiology, Department of Medicine, University of Chicago Medical Center, Chicago, Illinois. Electronic address: rlang@medicine.bsd.uchicago.edu.
University of Chicago Medical Center · USPhilips (Netherlands) · NLAssistance Publique – Hôpitaux de Paris · FR

Funding

MULTIDISCIPLINARY CARDIAC SCIENCEST32HL007381 · NHLBI · UNIVERSITY OF CHICAGO · PI JEANNE M DECARA, Yoav Gilad · 1985 to 2026
$12.5M
NHLBI NIH HHS T32 HL007381
6 · The paper itself

Abstract

backgroundAccurate visualization of cardiac valves and lesions by three-dimensional (3D) echocardiography is integral for optimal guidance of structural procedures and appropriate selection of closure devices. A new 3D rendering tool known as transillumination (TI), which integrates a virtual light source into the data set, was recently reported to effectively enhance depth perception and orifice definition. We hypothesized that adding the ability to adjust transparency to this tool would result in improved visualization and delineation of anatomy and pathology and improved localization of regurgitant jets compared with TI without transparency and standard 3D rendering.

methodsWe prospectively studied 30 patients with a spectrum of structural heart disease who underwent 3D transesophageal imaging (EPIQ system, Philips) with standard acquisition and TI with and without the transparency feature. Six experienced cardiologists and sonographers were shown randomized images of all three display types in a blinded fashion. Each image was scored independently by all experts using a Likert scale from 1 to 5, while assessing each of the following aspects: (1) ability to recognize anatomy, (2) ability to identify pathology, including regurgitant jet origin, (3) depth perception, and (4) quality of border delineation.

resultsTI images with transparency were successfully obtained in all cases. All experts perceived an incremental value of the transparency mode, compared with TI without transparency and standard 3D rendering, in terms of ability to recognize anatomy (respective scores: 4.5 ± 1.1 vs 4.1 ± 1.1 vs 3.6 ± 1.1, P < .05), ability to identify pathology (4.1 ± 1.1 vs 3.9 ± 1.2 vs 3.3 ± 1, P < .05), depth perception (4.6 ± 0.7 vs 4.1 ± 0.8 vs 3.2 ± 1.0, P < .05), and border delineation (4.6 ± 0.8 vs 4.1 ± 1.0 vs 3.1 ± 1.1, P < .05).

conclusionsThe addition of the transparency mode to TI rendering significantly improves the diagnostic and clinical utility of 3D echocardiography and has the potential to markedly enhance echocardiographic guidance of cardiac structural interventions.

Indexed as

Echocardiography, Three-DimensionalEchocardiographyEchocardiography, TransesophagealHeartHumansRandom AllocationThree-dimensional echocardiographyTransilluminationValvular heart disease

Identifiers

PMID32972777
PMCPMC7920620
OpenAlexW3089244743

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.