Evidence map›Paper›PMID 32972645›Full record

ArticleJournal of substance abuse treatment2020

Patterns of substance use before and after hospitalization among patients seen by an inpatient addiction consult service: A latent transition analysis.

Caroline King, Christina Nicolaidis, P Todd Korthuis, Kelsey C Priest, Honora Englander

Open access · greenAbstract read
In one paragraph

Article in Journal of substance abuse treatment, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Caroline KingDepartment of Biomedical Engineering, School of Medicine, Oregon Health & Science University, Portland, OR, United States of America; MD/PhD Program, School of Medicine, Oregon Health & Science University, Portland, OR, United States of America. Electronic address: kingca@ohsu.edu.
Christina NicolaidisSchool of Social Work, Portland State University, Portland, OR, United States of America; OHSU-PSU School of Public Health, Oregon Health & Science University, Portland, OR, United States of America; Division of General Internal Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR, United States of America.
P Todd KorthuisOHSU-PSU School of Public Health, Oregon Health & Science University, Portland, OR, United States of America; Division of General Internal Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR, United States of America.
Kelsey C PriestMD/PhD Program, School of Medicine, Oregon Health & Science University, Portland, OR, United States of America.
Honora EnglanderDivision of Hospital Medicine, Department of Medicine, Oregon Health & Science University, Portland, OR, United States of America.
Oregon Health & Science University · USOregon Health and Science University Hospital · US

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
Western States Node of the National Drug Abuse Treatment Clinical Trials NetworkU10DA015815 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MCCARTY, DENNIS, SORENSEN, JAMES L · 2002 to 2015
$25.2M
Western States Node of the National Drug Abuse Treatment Clinical Trials Network (TMS for CUD) UG1DA015815 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Keith N. Humphreys, Philip Todd Korthuis · 2015 to 2026
$24.6M
Buprenorphine to Improve HIV Care Engagement and Outcomes: A Randomized TrialR01DA037441 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI KORTHUIS, PHILIP TODD · 2013 to 2018
$2.7M
Variation in the Use of Opioid Agonist Treatment in HospitalsF30DA044700 · NIDA · OREGON HEALTH & SCIENCE UNIVERSITY · PI PRIEST, KELSEY CAROLINE · 2017 to 2020
$186k
NCATS NIH HHS UL1 TR002369NIDA NIH HHS F30 DA044700NIDA NIH HHS R01 DA037441NIDA NIH HHS U10 DA015815NIDA NIH HHS UG1 DA015815
6 · The paper itself

Abstract

BACKGROUND AND

aimsPolysubstance use is common and contributes to morbidity and mortality of hospitalized patients, and yet little is known about patterns of substance use among hospitalized patients, or how an addiction consult service (ACS) might impact polysubstance use after discharge. The objective of this study was to identify patterns of substance use at admission and after discharge among hospitalized patients with substance use disorders who saw an ACS.

designProspective cohort study. We used latent transition analysis of substance use scores at the time of hospital admission and 30 to 90 days posthospitalization.

settingSingle, academic health center with an ACS in Portland, Oregon, from 2015 to 2018. PARTICIPANTS/CASES: Patients were eligible if they received a consult to the inpatient ACS. MEASUREMENTS: We used Addiction Severity Index-Lite scores to capture self-reported substance use at baseline and follow-up for heroin, other opioid, alcohol, amphetamine, and cocaine.

findingsFrom 2015 to 2018, 486 individuals consented to participate. More than half of patients used more than one substance at baseline. Of those reporting any baseline opioid use, nearly three-quarters (n=187, 69.5%) had polysubstance use in the previous 30 days, including alcohol (n=80, 29.7%), cocaine (n=25, 9.3%), or amphetamine use (n=142, 52.8%). We identified three patterns of substance use at baseline: 1) alcohol use dominant, 2) polysubstance use dominant, and 3) heroin and other opioid use dominant. Patients transitioned along five trajectories to three different follow-up profiles that showed lower endorsement of all substances used. Slightly more than 40% (40.1%) of patients newly endorsed abstinence of at least one substance at follow-up.

conclusionsPolysubstance use is common in hospitalized patients with substance use disorders and identifying patterns of polysubstance use can guide clinical management. Hospital providers should prepare to manage polysubstance use during hospitalization and hospitals should broaden care beyond interventions for opioid use disorder.

Indexed as

Opioid-Related DisordersSubstance-Related DisordersHospitalizationHumansInpatientsOregonProspective StudiesAddictive behaviorAlcoholAmphetamineHospitalizationInpatientsOpioid-related disorders

Identifiers

PMID32972645
PMCPMC8244750
OpenAlexW3081348109

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.