Evidence map›Paper›PMID 32972572›Full record

ArticleJACC. Cardiovascular interventions2020

Predictors of Residual Right-to-Left Shunt After Percutaneous Suture-Mediated Patent Fossa Ovalis Closure.

Achille Gaspardone, Gregory A Sgueglia, Antonella De Santis, Emanuela D'Ascoli, Maria Iamele, Fabiana Piccioni, Benedetta Giannico, Fabrizio D'Errico, Gaetano Gioffrè, Francesco Summaria and 2 more

Abstract read
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In one paragraph

Article in JACC. Cardiovascular interventions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Treatment of patent foramen ovale.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Review
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  9. Review
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  15. A systematic transoesophageal echocardiography study of suture-mediated percutaneous patent foramen ovale closure.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Article
  16. Mechanisms of ineffective patent foramen ovale closure using the percutaneous suture-mediated NobleStitch system.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2022
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 1 country.

Achille GaspardoneDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy. Electronic address: a_gaspardone@yahoo.com.
Gregory A SguegliaDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Antonella De SantisDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Emanuela D'AscoliDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Maria IameleDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Fabiana PiccioniDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Benedetta GiannicoDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Fabrizio D'ErricoDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Gaetano GioffrèDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Francesco SummariaDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Carlo GaspardoneDivision of Cardiology, Sant'Eugenio Hospital, Rome, Italy.
Francesco VersaciDivision of Cardiology, Santa Maria Goretti Hospital, Latina, Italy.
St. Eugenio Hospital · ITOspedale Santa Maria Goretti · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study sought to assess patent fossa ovalis (PFO) anatomy by transesophageal echocardiography (TEE) in patients undergoing percutaneous suture-mediated PFO closure to identify predictors of post-procedural residual atrial right-to-left shunt (RLS).

backgroundPercutaneous suture-mediated PFO closure has been proven to be a safe and effective technique in most PFO patients.

methodsFrom June 2016 to October 2019, 247 consecutive patients underwent percutaneous suture-mediated PFO closure at our institution. Of them, 230 (46 ± 13 years of age, 146 women) had complete and technically evaluable pre-procedural TEE. The following parameters in short-axis view were assessed: presence and grade of spontaneous RLS, PFO length and width, presence of atrial septal aneurysm and its maximal bulge, and presence of an embryonic or fetal remnant (Chiari network or Eustachian valve).

resultsAt the first follow-up transthoracic echocardiography performed between 3 and 6 months from the closure procedure, a residual RLS ≥2 grade was found in 37 (16%) patients. Grade of pre-procedural spontaneous RLS (hazard ratio: 1.99; 95% confidence interval: 1.14 to 3.48; p = 0.016) shunt and PFO width (hazard ratio: 2.52; 95% confidence interval: 1.85 to 3.43; p < 0.001) were both found to be significantly associated with significant residual RLS at multivariable analysis. The presence of atrial septal aneurysm and its maximal bulge and of congenital remnants was not associated with significant residual RLS.

conclusionsPercutaneous suture-mediated PFO closure is feasible in the majority of septal anatomies; however, PFO >5 mm in width and spontaneous large RLS are less likely to be closed with 1 stitch only.

Indexed as

Foramen Ovale, PatentHeart AneurysmAdultCardiac CatheterizationEchocardiography, TransesophagealFemaleFollow-Up StudiesHumansMaleMiddle AgedSuturesTreatment Outcomeanatomypatent fossa ovalispercutaneous closuresuture

Identifiers

PMID32972572
OpenAlexW3088861149

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.